Evidence map›Paper›PMID 32890202›Full record

ArticleJournal of occupational and environmental medicine2020

Longitudinal Assessment of Health Symptoms in Relation to Neurotoxicant Exposures in 1991 Gulf War Veterans: The Ft. Devens Cohort.

Megan K Yee, Clara G Zundel, Alexis L Maule, Timothy Heeren, Susan P Proctor, Kimberly A Sullivan, Maxine H Krengel

Abstract read
In one paragraph

Article in Journal of occupational and environmental medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Megan K YeeResearch Service, VA Boston Healthcare System, Boston, Massachusetts (Yee, Zundel, Dr Proctor, Dr Krengel); Behavioral Neuroscience Program, Boston University School of Medicine, Boston, Massachusetts (Zundel); Department of Environmental Health, Boston University School of Public Health, Boston, Massachusetts (Drs Maule, Sullivan); Military Performance Division, US Army Research Institute of Environmental Medicine, Natick, Massachusetts (Drs Maule, Proctor); Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts (Dr Heeren); and Department of Neurology, Boston University School of Medicine, Boston, Massachusetts (Dr Krengel).
Clara G Zundel
Alexis L Maule
Timothy Heeren
Susan P Proctor
Kimberly A Sullivan
Maxine H Krengel

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis analysis examined the relationship between Gulf War (GW) exposures and health symptoms reported in three time periods over 20 years in Ft. Devens Cohort veterans.

methodsRepeated logistic regression models examined the association of exposures and health symptoms over time. Models included baseline age, active duty status, post-traumatic stress disorder status, sex, and time since deployment as covariates.

resultsExposure to tent heaters was associated with increased odds of crying easily and muscle twitching. Exposure to pyridostigmine bromide (PB) pills was associated with increased odds of depression and fatigue. Exposure to the Khamisiyah sarin plume was associated with increased odds of trouble concentrating and crying easily.

conclusionThis longitudinal analysis demonstrated an association between neurotoxicant exposures and increased odds of cognitive/mood, fatigue, and neurological symptoms. In addition, most symptoms increased over time since deployment regardless of exposure.

Indexed as

Persian Gulf SyndromeVeteransCohort StudiesGulf WarHumansLongitudinal StudiesNeurotoxinsOccupational ExposurePyridostigmine BromideSarinNeurotoxinsPyridostigmine BromideSarin

Identifiers

PMID32890202
PMCPMC7478220

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.