ReviewJournal of the American Academy of Orthopaedic Surgeons. Global research & reviews2020
Management of Osteomyelitis in Sickle Cell Disease: Review Article.
Review in Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 37 citations in OpenAlex.
- Mandibular Osteomyelitis and Acute Soft Head Syndrome in an Adolescent With Sickle Cell Disease.Journal of medical cases · 2026Article
- Challenges and Management Outcomes of Osteoarticular Infections in Adult Sickle Cell Disease Patients.Journal of clinical medicine · 2025Article
- Shoulder complications in sickle cell disease: Challenges, management strategies, and future directions.World journal of orthopedics · 2025Review
- Magnetic Resonance Imaging of Musculoskeletal Manifestations in Sickle Cell Disease.Journal of clinical medicine · 2025Article
- Automated radiosynthesis of [EJNMMI radiopharmacy and chemistry · 2025Article
- Imaging Modalities for Differentiating Bone Infarction and Osteomyelitis in Sickle Cell Disease: A Literature Review.Cureus · 2025Review
- Clinical Manifestations in the Maxillofacial Region of Acute Crisis of Sickle Cell Anemia: A Case Report.Journal of clinical and experimental dentistry · 2025Article
- Infections in sickle cell disease.Haematologica · 2025Review
- Sickle cell disease: suspect, check, diagnose-practical tips for non-SCD experts to suspect and diagnose SCD in low-prevalence European settings.Frontiers in medicine · 2025Review
- Biofilm-Induced Bone Degradation in Osteomyelitis:Sultan Qaboos University medical journal · 2025Article
- Bilaterally Symmetrical Serratia Osteomyelitis of Distal Third Radius in an Adolescent Female with Sickle Cell Disease: A Rare Case Report.Journal of orthopaedic case reports · 2024Article
- Indicators for Osteomyelitis in Children With Sickle Cell Disease Admitted With Vaso-Occlusive Crises.Cureus · 2024Article
- [Infectious, pathologic humeral fracture in a patient with sickle cell disease-A rare case?]Unfallchirurgie (Heidelberg, Germany) · 2024Article
- Predictors of Developing a Complex Course of Osteomyelitis in Patients with Sickle Cell Anaemia.Sultan Qaboos University medical journal · 2024Article
- Unique Bilaterally Symmetrical Multifocal Osteomyelitis Presentation in a Health-care Worker with Sickle Cell Disease Secondary to Klebsiella Infection - A Case Report.Journal of orthopaedic case reports · 2024Article
- Article
- Subperiosteal Orbital Hematoma: A Rare Clinical Manifestation of Sickle Cell Disease - A Case Report.Case reports in ophthalmologyArticle
- Noah's Ark Phenomenon in Medicine: A Novel Description of Clustering of Clinical Conditions, the Surgical Perspective.Journal of the West African College of SurgeonsReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sickle cell disease (SCD) is an autosomal recessive disorder that is characterized by abnormal "sickle-shaped" erythrocytes. Because of their shape, these erythrocytes are more likely to become trapped in small slow-flowing vessels, leading to vaso-occlusion. Because this commonly happens in the bones, patients with SCD are at an increased risk for orthopaedic manifestations such as osteomyelitis, septic joint, or osteonecrosis. Osteomyelitis is a serious and potentially disabling condition but can be difficult to differentiate from benign conditions of SCD, such as vaso-occlusive crisis. Diagnosis of osteomyelitis requires careful evaluation of the clinical presentation, laboratory testing, and imaging. Treatment of osteomyelitis in patients with SCD may be medical or surgical, but considerations in antibiotic selection and management preoperatively and postoperatively must be taken to ensure optimal outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.