ArticleMolecular plant2020
Phosphorylation of the Pseudomonas Effector AvrPtoB by Arabidopsis SnRK2.8 Is Required for Bacterial Virulence.
Article in Molecular plant, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 49 citations in OpenAlex.
- A novel approach to enhance resistance to vascular disease by expressing cell-death-inducing fungal elicitors in the xylem tissue.Plant biotechnology journal · 2025Article
- Wheat tandem kinase RWT4 directly binds a fungal effector to activate defense.Nature genetics · 2025Article
- A SnRK2-HAK regulatory module confers natural variation of salt tolerance in maize.Nature communications · 2025Article
- Interplay Between ROS and Hormones in Plant Defense Against Pathogens.Plants (Basel, Switzerland) · 2025Review
- SnRK2s: Kinases or Substrates?Plants (Basel, Switzerland) · 2025Review
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- Abscisic Acid Can Play a Dual Role in thePlants (Basel, Switzerland) · 2025Article
- A viral protein activates the MAPK pathway to promote viral infection by downregulating callose deposition in plants.Nature communications · 2024Article
- Nuclear localization sequence of MoHTR1, a Magnaporthe oryzae effector, for transcriptional reprogramming of immunity genes in rice.Nature communications · 2024Article
- Two transcription factors, AcREM14 and AcC3H1, enhance the resistance of kiwifruitHorticulture research · 2024Article
- Multiple host targets ofbioRxiv : the preprint server for biology · 2023Article
- Exogenous Ca2+ promotes transcription factor phosphorylation to suppress ethylene biosynthesis in apple.Plant physiology · 2023Article
- Article
- Plant immune receptors interact with hemibiotrophic pathogens to activate plant immunity.Frontiers in microbiology · 2023Review
- What's new in protein kinase/phosphatase signalling in the control of plant immunity?Essays in biochemistry · 2022Review
- Identification of effector CEP112 that promotes the infection of necrotrophic Alternaria solani.BMC plant biology · 2022Article
- A bacterial effector counteracts host autophagy by promoting degradation of an autophagy component.The EMBO journal · 2022Article
- Pathogen effectors: What do they do at plasmodesmata?Molecular plant pathology · 2022Review
- Examining the genomic features of human and plant-associated Burkholderia strains.Archives of microbiology · 2022Article
- Ubiquitination of Receptorsomes, Frontline of Plant Immunity.International journal of molecular sciences · 2022Review
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
A critical component controlling bacterial virulence is the delivery of pathogen effectors into plant cells during infection. Effectors alter host metabolism and immunity for the benefit of pathogens. Multiple effectors are phosphorylated by host kinases, and this posttranslational modification is important for their activity. We sought to identify host kinases involved in effector phosphorylation. Multiple phosphorylated effector residues matched the proposed consensus motif for the plant calcium-dependent protein kinase (CDPK) and Snf1-related kinase (SnRK) superfamily. The conserved Pseudomonas effector AvrPtoB acts as an E3 ubiquitin ligase and promotes bacterial virulence. In this study, we identified a member of the Arabidopsis SnRK family, SnRK2.8, which interacts with AvrPtoB in yeast and in planta. We showed that SnRK2.8 was required for AvrPtoB virulence functions, including facilitating bacterial colonization, suppression of callose deposition, and targeting the plant defense regulator NPR1 and analyses receptor FLS2. Mass spectrometry analysis revealed that AvrPtoB phosphorylation occurs at multiple serine residues in planta, with S258 phosphorylation significantly reduced in the snrk2.8 knockout. AvrPtoB phospho-null mutants exhibited compromised virulence functions and were unable to suppress NPR1 accumulation, FLS2 accumulation, or inhibit FLS2-BAK1 complex formation upon flagellin perception. Taken together, these data identify a conserved plant kinase utilized by a pathogen effector to promote disease.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.