Evidence map›Paper›PMID 32888507›Full record

ArticleAmerican journal of human genetics2020

The Role of Age-Related Clonal Hematopoiesis in Genetic Sequencing Studies.

Henne Holstege, Marc Hulsman, Sven J van der Lee, Erik B van den Akker

Open access · bronzeAbstract readLetterComment
In one paragraph

Article in American journal of human genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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  3. Review
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  6. Response to Holstege et al.American journal of human genetics · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Henne HolstegeDepartment of Clinical Genetics, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands; Pattern Recognition & Bioinformatics, Delft University of Technology, Delft 2628CD, the Netherlands. Electronic address: h.holstege@amsterdamumc.nl.
Marc HulsmanDepartment of Clinical Genetics, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands; Pattern Recognition & Bioinformatics, Delft University of Technology, Delft 2628CD, the Netherlands.
Sven J van der LeeDepartment of Clinical Genetics, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands; Pattern Recognition & Bioinformatics, Delft University of Technology, Delft 2628CD, the Netherlands.
Erik B van den AkkerPattern Recognition & Bioinformatics, Delft University of Technology, Delft 2628CD, the Netherlands; Leiden Computational Biology Center, Leiden University Medical Center, Leiden 2300RC, the Netherlands; Section of Molecular Epidemiology, Leiden University Medical Center, Leiden 2300RC, the Netherlands.
Amsterdam Neuroscience · NLLeiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Neurodegenerative DiseasesDioxygenasesDNA-Binding ProteinsHematopoiesisHigh-Throughput Nucleotide SequencingHumansProto-Oncogene ProteinsDioxygenasesDNA-Binding ProteinsProto-Oncogene ProteinsTET2 protein, human

Identifiers

PMID32888507
PMCPMC7477003
OpenAlexW3083365393

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.