Evidence map›Paper›PMID 32888480›Full record

Observational studyCurrent biology : CB2020

Cortical Encoding of Manual Articulatory and Linguistic Features in American Sign Language.

Matthew K Leonard, Ben Lucas, Shane Blau, David P Corina, Edward F Chang

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Current biology : CB, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Ten things you should know about sign languages.Current directions in psychological science · 2023
    Article
  5. Article
  6. Fingerspelling and Its Role in Translanguaging.Languages (Basel, Switzerland) · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Matthew K LeonardDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, USA; Center for Integrative Neuroscience, University of California, San Francisco, San Francisco, CA, USA; Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.
Ben LucasDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, USA; Center for Integrative Neuroscience, University of California, San Francisco, San Francisco, CA, USA; Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.
Shane BlauCenter for Mind and Brain, University of California, Davis, Davis, CA, USA; Department of Linguistics, University of California, Davis, Davis, CA, USA.
David P CorinaCenter for Mind and Brain, University of California, Davis, Davis, CA, USA; Department of Linguistics, University of California, Davis, Davis, CA, USA.
Edward F ChangDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, USA; Center for Integrative Neuroscience, University of California, San Francisco, San Francisco, CA, USA; Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA. Electronic address: edward.chang@ucsf.edu.

Funding

Functional organization of the superior temporal gyrus for speech perceptionR01DC012379 · NIDCD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Edward Chang · 2012 to 2026
$8.3M
Functional Architecture of Human Speech Motor CortexDP2OD008627 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHANG, EDWARD · 2011 to 2011
$2.3M
Neural Basis of Gestural Communication: Evidence from Sign LanguageR01DC011538 · NIDCD · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI BELLUGI, URSULA, CORINA, DAVID P · 2012 to 2016
$2.0M
Diversity Supplement to R01DC014767R01DC014767 · NIDCD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CORINA, DAVID P · 2015 to 2019
$1.7M
Neocortical Mechanisms of Categorical Speech PerceptionR00NS065120 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHANG, EDWARD · 2010 to 2012
$729k
The Neurophysiological Dynamics of Lexical and Sub-Lexical RepresentationsF32DC013486 · NIDCD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LEONARD, MATTHEW KANTER · 2013 to 2016
$168k
NIDCD NIH HHS F32 DC013486NIDCD NIH HHS R01 DC011538NIDCD NIH HHS R01 DC012379NIDCD NIH HHS R01 DC014767NIH HHS DP2 OD008627NINDS NIH HHS R00 NS065120
6 · The paper itself

Abstract

The fluent production of a signed language requires exquisite coordination of sensory, motor, and cognitive processes. Similar to speech production, language produced with the hands by fluent signers appears effortless but reflects the precise coordination of both large-scale and local cortical networks. The organization and representational structure of sensorimotor features underlying sign language phonology in these networks remains unknown. Here, we present a unique case study of high-density electrocorticography (ECoG) recordings from the cortical surface of profoundly deaf signer during awake craniotomy. While neural activity was recorded from sensorimotor cortex, the participant produced a large variety of movements in linguistic and transitional movement contexts. We found that at both single electrode and neural population levels, high-gamma activity reflected tuning for particular hand, arm, and face movements, which were organized along dimensions that are relevant for phonology in sign language. Decoding of manual articulatory features revealed a clear functional organization and population dynamics for these highly practiced movements. Furthermore, neural activity clearly differentiated linguistic and transitional movements, demonstrating encoding of language-relevant articulatory features. These results provide a novel and unique view of the fine-scale dynamics of complex and meaningful sensorimotor actions.

Indexed as

Sign LanguageBrain MappingBrain NeoplasmsElectric StimulationElectrocorticographyElectrodesGlioblastomaHumansLinguisticsMaleMiddle AgedSensorimotor CortexSingle-Case Studies as TopicUnited Statesdeafdirect electrical stimulationelectrocorticographysensorimotor controlsign language

Identifiers

PMID32888480
PMCPMC7674262

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.