ArticlePlant biotechnology journal2021
Mediation of JA signalling in glandular trichomes by the woolly/SlMYC1 regulatory module improves pest resistance in tomato.
Article in Plant biotechnology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed, 113 citations in OpenAlex.
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- Plant strategies against herbivorous insects.Journal of integrative plant biology · 2026Review
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- A comparative framework for trichome and trichome-derived epidermal appendage development across model glycophytes and halophytes.Plant cell reports · 2026Review
- Insights into glandular trichome biology from analysis of organ-specific gene expression programmes in cannabis, hop and tomato.The Plant journal : for cell and molecular biology · 2026Article
- The Genetic Wiring of Plant Trichomes: From Initiation to Fate Specification.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Integrative chromosome-level genomics and metabolomics uncover regulatory networks linking monoterpenoid biosynthesis and glandular trichome formation inHorticulture research · 2026Article
- Robustness in jasmonate signaling: mechanisms of concerted regulation and implications for crop improvement.aBIOTECH · 2025Review
- The role, regulation and application of plant fruit trichomes.Molecular horticulture · 2025Review
- Glutathionylation-mediated degradation of a cap-binding protein enhances Arabidopsis resistance to Plutella xylostella.The Plant cell · 2025Article
- JA-Mediated Regulation of Amino Acid Homeostasis Adjusts Metabolic Flux and Enhances Spider Mite Tolerance via the SlJAZ8-SlWRKY57-SlAVT6s Module in Tomato.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Unraveling the Complexity of Plant Trichomes: Models, Mechanisms, and Bioengineering Strategies.International journal of molecular sciences · 2025Review
- Glandless, a tomato HD-ZIP transcription factor, is important for the gland formation of type VI trichomes.The Plant journal : for cell and molecular biology · 2025Article
- CRISPR/Cas9-mediated editing of jasmonic acid pathways to enhance biotic & abiotic stress tolerance: An overview & prospects.Functional & integrative genomics · 2025Review
- The SlGRAS9-SlMYC1 regulatory module controls glandular trichome formation and modulates resilience to pest in tomato.The Plant journal : for cell and molecular biology · 2025Article
- The Role of MYC2 Transcription Factors in Plant Secondary Metabolism and Stress Response Mechanisms.Plants (Basel, Switzerland) · 2025Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Almost all plants form trichomes, which protect them against insect herbivores by forming a physical barrier and releasing chemical repellents. Glandular trichomes produce a variety of specialized defensive metabolites, including volatile terpenes. Previous studies have shown that the defence hormone jasmonic acid (JA) affects trichome development and induces terpene synthases (TPSs) but the underlying molecular mechanisms remain unclear. Here, we characterized a loss-of-function allele of the HD-ZIP IV transcription factor woolly (wo) and analysed its role in mediating JA signalling in tomato. We showed that knockout of wo led to extensive trichome defects, including structural and functional changes in type VI glandular trichomes, and a dramatic reduction in terpene levels. We further found that wo directly binds to TPS gene promoters to recruit SlMYC1, a JA signalling modulator, and that together these transcription factors promote terpene biosynthesis in tomato trichomes. The wo/SlMYC1 regulatory module is inhibited by SlJAZ2 through a competitive binding mechanism, resulting in a fine-tuned JA response in tomato trichomes. Enhanced expression of SlMYC1 substantially increased terpene levels and improved tomato resistance to spider mites. Interestingly, we also found that SlMYC1 plays an additional role in glandular cell division and expansion in type VI trichomes, independent of JA. Together, our results reveal a novel, JA-mediated regulatory mechanism that promotes insect resistance in tomato.
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