Evidence map›Paper›PMID 32888083›Full record

ArticleMikrochimica acta2020

Flow injection enzymatic biosensor for aldehydes based on a Meldola Blue-Ni complex electrochemical mediator.

Ana Maria Titoiu, Georgiana Necula-Petrareanu, Diana Visinescu, Valentina Dinca, Anca Bonciu, Cristian N Mihailescu, Cristina Purcarea, Rabah Boukherroub, Sabine Szunerits, Alina Vasilescu

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In one paragraph

Article in Mikrochimica acta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Ana Maria TitoiuInternational Centre of Biodynamics, 1B Intrarea Portocalelor, 060101, Bucharest, Romania.
Georgiana Necula-PetrareanuInstitute of Biology, 296 Splaiul Independentei, 060031, Bucharest, Romania.
Diana VisinescuCoordination and Supramolecular Chemistry Laboratory, "Ilie Murgulescu" Institute of Physical Chemistry, Romanian Academy, Splaiul Independentei 202, 060021, Bucharest, Romania.
Valentina DincaNational Institute for Laser, Plasma and Radiation Physics (INFLPR), 409 Atomistilor, 077125, Magurele, Romania.
Anca BonciuNational Institute for Laser, Plasma and Radiation Physics (INFLPR), 409 Atomistilor, 077125, Magurele, Romania.
Cristian N MihailescuNational Institute for Laser, Plasma and Radiation Physics (INFLPR), 409 Atomistilor, 077125, Magurele, Romania.
Cristina PurcareaInstitute of Biology, 296 Splaiul Independentei, 060031, Bucharest, Romania.
Rabah BoukherroubUniv. Lille, CNRS, Centrale Lille, Univ. Polytechnique Hauts-de-France, UMR 8520 - IEMN, F-59000, Lille, France.
Sabine SzuneritsUniv. Lille, CNRS, Centrale Lille, Univ. Polytechnique Hauts-de-France, UMR 8520 - IEMN, F-59000, Lille, France.
Alina VasilescuInternational Centre of Biodynamics, 1B Intrarea Portocalelor, 060101, Bucharest, Romania. avasilescu@biodyn.ro.ORCID https://orcid.org/0000-0002-2492-0819
Centre National de la Recherche Scientifique · FRInternational Centre of Biodynamics · RONational Institute for Laser Plasma and Radiation Physics · RORomanian Academy · ROUniversity of Bucharest · RO

Funding

UEFISCDI ERANET-M-ENZ4IFACES, contract 166 /01.05.2020UEFISCDI PN-III-P2-2.1-PED-2016-0116
6 · The paper itself

Abstract

Carbon nanofibers (CNF) are efficient electrode modifiers in electrochemical biosensors that enhance the electrochemical active area, induce electrocatalytic effect toward the oxidation of the enzymatic cofactor nicotinamide adenine dinucleotide (reduced form, NADH), and enable the quantitative immobilization of enzymes. Combining CNF with efficient and stable mediators radically augments the speed of electron transfer between NADH and solid electrodes and leads to electrochemical sensors characterized by high sensitivity and stability. The main aim of this work was to investigate the performance of a novel mediator for NADH with advantageously low solubility in an electrochemical detector based on a screen-printed CNF electrode as well as its potential in biosensing. Using a mediator, prepared from Meldola Blue and Ni hexamine chloride, a stable and sensitive electrochemical NADH sensor is provided with a detection limit of 0.5 μmol L

Indexed as

Biosensing TechniquesElectrochemistryOxazinesMeldola blueOxazinesAldehyde dehydrogenaseBenzaldehyde sensingCarbon nanofibersElectrochemical mediatorFlow injection analysisNADH

Identifiers

PMID32888083
OpenAlexW3083550615

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.