Evidence map›Paper›PMID 32888077›Full record

SynthesisNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2021

Serum vascular endothelial growth factor (VEGF) levels in ischemic stroke patients: a systematic review and meta-analysis of case-control studies.

Ali Seidkhani-Nahal, Afra Khosravi, Asad Mirzaei, Gholam Basati, Milad Abbasi, Ali Noori-Zadeh

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Clinical, Imaging, and Serum Biomarker Predictors of Malignant Cerebral Infarction.Journal of cardiovascular development and disease · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Neovascularization and tissue regeneration by endothelial progenitor cells in ischemic stroke.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ali Seidkhani-NahalDepartment of Clinical Biochemistry, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.
Afra KhosraviDepartment of Clinical Immunology, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.
Asad MirzaeiDepartment of Medical Parasitology, Faculty of Allied Medical Sciences, Ilam University of Medical Sciences, Ilam, Iran.
Gholam BasatiDepartment of Clinical Biochemistry, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.
Milad AbbasiStudent Research Committee, Ilam University of Medical Sciences, Ilam, Iran.
Ali Noori-ZadehStudent Research Committee, Ilam University of Medical Sciences, Ilam, Iran. noorizadeh-a@medilam.ac.ir.ORCID http://orcid.org/0000-0002-4897-7684
Medical University of Ilam · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serum VEGF level is regarded to be a biomarker for the diagnosis of stroke. Even though there have been published plethora of original articles describing higher blood VEGF concentrations since the 1970s, however, there is no any meta-analysis report for serum VEGF levels in the field of evidence-based medicine yet. A systematic review was performed by searching the online biomedical databases including retrieving 14 case-control studies including within-article subgroups after fulfilling the inclusion and exclusion criteria without the beginning date restriction, until 2020 for ischemic stroke patients. The Q quantity and I

Indexed as

Brain IschemiaIschemic StrokeStrokeCase-Control StudiesHumansVascular Endothelial Growth Factor AVascular Endothelial Growth FactorsVascular Endothelial Growth Factor AVascular Endothelial Growth FactorsHemorrhagic strokeIschemic strokeMeta-analysisSerum biomarkerVEGF

Identifiers

PMID32888077
OpenAlexW3083425979

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.