Evidence map›Paper›PMID 32888057›Full record

ArticleEuropean journal of applied physiology2020

The inclusion of interstimulus interval variability does not mitigate electrically-evoked fatigue of the knee extensors.

Alexandra F Yacyshyn, Robin B Huculak, Chris J McNeil

Abstract read
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In one paragraph

Article in European journal of applied physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Alexandra F YacyshynSchool of Health and Exercise Sciences, Faculty of Health and Social Development, The University of British Columbia, Okanagan Campus, 133-1147 Research Road, Kelowna, BC, V1V 1V7, Canada.ORCID https://orcid.org/0000-0002-9787-7225
Robin B HuculakSchool of Health and Exercise Sciences, Faculty of Health and Social Development, The University of British Columbia, Okanagan Campus, 133-1147 Research Road, Kelowna, BC, V1V 1V7, Canada.
Chris J McNeilSchool of Health and Exercise Sciences, Faculty of Health and Social Development, The University of British Columbia, Okanagan Campus, 133-1147 Research Road, Kelowna, BC, V1V 1V7, Canada. chris.mcneil@ubc.ca.ORCID http://orcid.org/0000-0003-3681-4404
University of British Columbia · CAInterior Health · CA

Funding

British Columbia Knowledge Development Fund 32260Canadian Foundation for Innovation 32260Natural Sciences and Engineering Research Council of Canada DG 435912-2013
6 · The paper itself

Abstract

purposeTranscutaneous electrical stimulation (TES) is used to activate muscles when volitional capacity is impaired but potential benefits are limited by rapid force loss (fatigue). Most TES fatigue protocols employ constant-frequency trains, with stimuli at a fixed interstimulus interval (ISI); however, a brief ISI between the first two pulses (variable-frequency train, VFT) to maximize the catchlike property of muscle can attenuate fatigue development. The purpose of this study was to investigate if a VFT that simulates intrinsic variability of voluntary motor unit discharge rates would also mitigate fatigue, owing to the sensitivity of muscle to acute activation history.

methodsOn two visits, 24 healthy adults (25.3 ± 3.7 years; 12 females) received 3 min of intermittent TES to the quadriceps of the dominant leg. Trains of eight pulses at 10 Hz were delivered with a constant (100 ms) or variable ISI (80-120 ms). Contractile impulse, rate of force development (RFD), and rate of relaxation (RFR) were determined for each tetanus

resultsDuring fatigue and recovery, contractile impulse did not differ between protocols (p ≥ 0.796) and sexes (p ≥ 0.493), with values of 77 ± 17% control at task end and 125 ± 19% control 2 min later. RFD and RFR also showed no effect of the protocol (p ≥ 0.310) or participant sex (p ≥ 0.119). Both measures slowed (38 ± 23% and 33 ± 22%, respectively) but dissociated during recovery as RFD remained 16 ± 18% below control at 5 min, whereas RFR recovered to control by 30 s (101 ± 22%).

conclusionContrary to expectations, the VFT protocol did not attenuate fatigue development, which suggests no benefit to mimicking the inherent variability of motor unit discharge rates.

Indexed as

AdultElectric StimulationFemaleHumansKnee JointMaleMuscle ContractionMuscle FatigueMuscle, SkeletalConstant-frequency trainPeripheral fatigueQuadricepsSex-related differencesTranscutaneous electrical stimulationVariable-frequency train

Identifiers

PMID32888057
OpenAlexW3083596204

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.