Evidence map›Paper›PMID 32887748›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

Immunization with

Claus Aagaard, Niels Peter Hell Knudsen, Iben Sohn, Angelo A Izzo, Hongmin Kim, Emma Holsey Kristiansen, Thomas Lindenstrøm, Else Marie Agger, Michael Rasmussen, Sung Jae Shin and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.5field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Article
  3. Anti-TB Drugs for Drug-Sensitive and Drug-ResistantCurrent issues in molecular biology · 2025
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Efficacy of light chain 3-fused protein multi epitope in protection of mice challenged withVeterinary research forum : an international quarterly journal · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. mBio · 2021
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Claus AagaardDepartment of Infectious Disease Immunology, Statens Serum Institut, DK-2300 Copenhagen, Denmark.ORCID 0000-0001-6433-3056
Niels Peter Hell KnudsenDepartment of Infectious Disease Immunology, Statens Serum Institut, DK-2300 Copenhagen, Denmark.ORCID 0000-0003-1400-5657
Iben SohnDepartment of Infectious Disease Immunology, Statens Serum Institut, DK-2300 Copenhagen, Denmark.
Angelo A IzzoColorado State University, Department of Microbiology, Immunology and Pathology, Fort Collins, CO 80523.ORCID 0000-0003-3208-2330
Hongmin KimDepartment of Microbiology, Institute for Immunology and Immunological Diseases, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul 03722, South Korea.ORCID 0000-0002-9215-2831
Emma Holsey KristiansenDepartment of Infectious Disease Immunology, Statens Serum Institut, DK-2300 Copenhagen, Denmark.
Thomas LindenstrømDepartment of Infectious Disease Immunology, Statens Serum Institut, DK-2300 Copenhagen, Denmark.ORCID 0000-0002-7162-8124
Else Marie AggerDepartment of Infectious Disease Immunology, Statens Serum Institut, DK-2300 Copenhagen, Denmark.
Michael RasmussenInternational Reference Laboratory of Mycobacteriology, Statens Serum Institut, DK-2300 Copenhagen, Denmark; and.ORCID 0000-0002-4401-7598
Sung Jae ShinDepartment of Microbiology, Institute for Immunology and Immunological Diseases, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul 03722, South Korea.
Ida RosenkrandsDepartment of Infectious Disease Immunology, Statens Serum Institut, DK-2300 Copenhagen, Denmark.
Peter AndersenDepartment of Infectious Disease Immunology, Statens Serum Institut, DK-2300 Copenhagen, Denmark.
Rasmus MortensenDepartment of Infectious Disease Immunology, Statens Serum Institut, DK-2300 Copenhagen, Denmark; rjm@ssi.dk.ORCID 0000-0003-0177-3032
Statens Serum Institut · DKYonsei University · KRColorado State University · US

Funding

A dual function TB subunit vaccine designed for non-interference with BCG and post-exposure activityR01AI135721 · NIAID · STATENS SERUM INSTITUTE · PI MORTENSEN, RASMUS SKAARUP · 2018 to 2022
$3.5M
NIAID NIH HHS HHSN272201000009INIAID NIH HHS R01 AI135721
6 · The paper itself

Abstract

Despite the fact that the majority of people in tuberculosis (TB)-endemic areas are vaccinated with the Bacillus Calmette-Guérin (BCG) vaccine, TB remains the leading infectious cause of death. Data from both animal models and humans show that BCG and subunit vaccines induce T cells of different phenotypes, and little is known about how BCG priming influences subsequent booster vaccines. To test this, we designed a novel

Indexed as

T-LymphocytesTuberculosisAnimalsAntigens, BacterialCell DifferentiationFemaleGuinea PigsMiceMycobacterium bovisMycobacterium tuberculosisVaccinationAntigens, Bacterial

Identifiers

PMID32887748
PMCPMC7533711
OpenAlexW3083608073

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.