Evidence map›Paper›PMID 32887746›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

Spatial Organization and Dynamics of the Extracellular Space in the Mouse Retina.

Sidney P Kuo, Pei-Pei Chiang, Amy R Nippert, Eric A Newman

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Osmotic Pressure and Its Biological Implications.International journal of molecular sciences · 2024
    Review
  5. On the Cranial Nerves.NeuroSci · 2024
    Review
  6. Fluorescence microscopy shadow imaging for neuroscience.Frontiers in cellular neuroscience · 2024
    Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sidney P KuoDepartment of Neuroscience, University of Minnesota, Minneapolis, Minnesota 55455.
Pei-Pei ChiangDepartment of Neuroscience, University of Minnesota, Minneapolis, Minnesota 55455.
Amy R NippertDepartment of Neuroscience, University of Minnesota, Minneapolis, Minnesota 55455.
Eric A NewmanDepartment of Neuroscience, University of Minnesota, Minneapolis, Minnesota 55455 ean@umn.edu.ORCID 0000-0002-9296-6237
University of Minnesota · US

Funding

Visual TestingP30EY011374 · NEI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI NEWMAN, ERIC A · 1996 to 2019
$8.8M
Regulation of Capillary Blood Flow in the Retina in Health and in Diabetic RetinopathyR01EY026514 · NEI · UNIVERSITY OF MINNESOTA · PI NEWMAN, ERIC A · 2016 to 2020
$1.9M
Glial cell regulation of blood flow in capillariesR01EY026882 · NEI · UNIVERSITY OF MINNESOTA · PI NEWMAN, ERIC A · 2016 to 2020
$1.7M
Training Program in Translational Vision SciencesT32EY025187 · NEI · UNIVERSITY OF MINNESOTA · PI Glenn P Lobo, LINDA K. MCLOON · 2016 to 2026
$1.2M
NEI NIH HHS P30 EY011374NEI NIH HHS R01 EY026514NEI NIH HHS R01 EY026882NEI NIH HHS T32 EY025187
6 · The paper itself

Abstract

The extracellular space (ECS) plays an important role in the physiology of neural circuits. Despite our detailed understanding of the cellular architecture of the mammalian retina, little is known about the organization and dynamics of the retinal ECS. We developed an optical technique based on two-photon imaging of fluorescently labeled extracellular fluid to measure the ECS volume fraction (α) in the

Indexed as

Absorptiometry, PhotonAnimalsAnimals, NewbornExtracellular SpaceFemaleFluorescent DyesMaleMiceMice, Inbred C57BLNeural PathwaysNeuronsOsmotic PressurePhotic StimulationRetinaRetinal Ganglion CellsFluorescent Dyesdiffusionextracellular spaceglial cellslight responseretinavolume fraction

Identifiers

PMID32887746
PMCPMC7548700
OpenAlexW3083685269

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.