ArticleHealth and quality of life outcomes2020
Factors affecting health-related quality of life in patients with skin disease: cross-sectional results from 8,789 patients with 16 skin diseases.
Article in Health and quality of life outcomes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Body image and mental health in chronic skin conditions: A psychosomatic perspective from a systematic review.Applied psychology. Health and well-being · 2025Pooled it
- Psychological and behavioral burden of scabies: a comprehensive cross-sectional analysis of pruritus, anxiety, behavioral adaptation, and quality of life.BMC primary care · 2026Article
- The Impact of Disease-Related Fear and Internalized Stigma on Quality of Life in Patients with Scabies: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- A mixed-methods online survey approach using retrospective self-reporting to characterise congenital ichthyoses across age groups.Orphanet journal of rare diseases · 2026Article
- Sleep quality and quality of life in patients with dermatological diseases during the war in Gaza.Scientific reports · 2026Article
- Article
- Economic burden and health-related quality of life in Chinese patients with mycosis fungoides and Sézary syndrome.Cancer pathogenesis and therapy · 2025Article
- Recent progress in the identification and in vitro culture of skin organoids.Regenerative therapy · 2025Review
- Psychiatric disorders in psoriatic patients: a cross-sectional study in multi-government hospitals.Archives of dermatological research · 2025Article
- Barriers to Skin Cancer Diagnosis and Treatment in Low- and Middle-Income Countries and Solutions: A Literature Review.Public health challenges · 2025Review
- Quality of life among adults with scabies: A community-based cross-sectional study in north-western Ethiopia.PLoS neglected tropical diseases · 2024Article
- Quality of life of dermatology outpatients and its associated factors in Halibet National Referral Hospital in Asmara, Eritrea.Scientific reports · 2024Article
- Dietary Antioxidants May Support Cosmetic Treatment in Patients with Rosacea.Antioxidants (Basel, Switzerland) · 2024Article
- Common Skin Diseases and Their Psychosocial Impact among Jazan Population, Saudi Arabia: A Cross-Sectional Survey during 2023.Medicina (Kaunas, Lithuania) · 2023Observational
- Quality of Life and Its Associated Factors among Patients with Psoriasis in a Semi-Urban Northeast Malaysia.International journal of environmental research and public health · 2022Article
- Generation and characterization of hair-bearing skin organoids from human pluripotent stem cells.Nature protocols · 2022Review
- Cellular metabolism changes in bilateral hippocampi in patients with herpes zoster.American journal of translational research · 2022Article
- Treatment Effect of Mometasone Furoate Cream on Lichen Sclerosus et Atrophicus of External Genitalia in Boys and Its Correlation with Toll-Like Receptor 4 and Myeloid Differentiation Factor 88.Journal of healthcare engineering · 2022Article
- Validation of the Persian version of Skindex-16 among older patients with skin diseases.BMC geriatrics · 2021Article
- Utilization of health services for skin disorders during military operations. A population- based study.Dermatology reports · 2020Article
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12 authors.
Funding
Abstract
backgroundMany previous studies have reported factors that contribute to health-related quality of life (HRQoL) for a single skin disease. However, little is known about generalized factors associated with HRQoL across skin diseases. The objective of this study was to investigate overall HRQoL, and to identify factors related to severely impaired HRQoL among patients with 16 different skin diseases.
methodsA cross-sectional study of 9845 patients with skin disease was conducted in 9 hospitals in China. HRQoL was assessed with the Chinese version of the Skindex-29 which measures dermatology-specific health along three domains (symptoms, emotions and functioning). With the published Skindex-29 cut-off scores for severely impaired HRQoL, logistic regression models assessed the relationship between severely impaired HRQoL and demographic/clinical characteristics, with adjustments for different skin diseases. To guarantee the models' convergence, 16 skin diseases with frequencies of at least 100 were included, and the sample size was 8789.
resultsEmotions was the most impaired aspect of HRQoL. Co-existing chronic diseases, 3 years or longer duration, and more severity were identified as associated factors for severely impaired HRQoL for each Skindex-29 domain, and for the aggregate. Being female, under 45 years old, and consuming alcohol were associated with a severely impaired emotion domain; Lack of exercise and smoking were associated with severely impaired symptoms and function domains, respectively.
conclusionsSkin diseases can affect many facets of HRQoL, but the emotional impairment deserves more attention. In addition to skin disease severity, this study shows that other chronic diseases and long duration are correlated with severely impaired HRQoL for patients with 16 clinical common skin diseases. This suggests the need for increased awareness in treating skin disease as a chronic disease. It also suggests that disease management decisions should consider HRQoL improvement, especially emotional conditions, when making management decisions.
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