ArticleGut microbes2020
Lactose-reduced infant formula with added corn syrup solids is associated with a distinct gut microbiota in Hispanic infants.
Article in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 29 citations in OpenAlex.
- Carbohydrate composition of infant formula and glycemic regulation in early infancy using continuous glucose monitoring: cross-sectional evidence of altered glucose patterns with corn syrup solid-based formulas.The American journal of clinical nutrition · 2026Observational
- Food and Drug Administration Expert Panel on Infant Formula "Operation Stork Speed" June 2025: Part 1, Nutrient Considerations.Advances in nutrition (Bethesda, Md.) · 2026Review
- Term infant formula macronutrient composition: An update for clinicians.Journal of pediatric gastroenterology and nutrition · 2025Review
- Maternal Diet Associated with Oligosaccharide Abundances in Human Milk from Latina Mothers.Nutrients · 2024Article
- The neighborhood food environment modifies the association between infant feeding and childhood obesity.BMC public health · 2024Article
- Influence of infant microbiome on health and development.Clinical and experimental pediatrics · 2024Article
- The Impact of Excessive Fructose Intake on Adipose Tissue and the Development of Childhood Obesity.Nutrients · 2024Review
- Any Infant Formula Amount, but Not Infant Formula Type, Is Associated with Less Healthful Subsequent Beverage Intake among Special Supplemental Nutrition Program for Women, Infants, and Children-Participating Children.Current developments in nutrition · 2024Article
- Altered Nutrient Composition of Lactose-Reduced Infant Formula.Nutrients · 2024Article
- Metatranscriptomic Analyses Reveal Important Roles of the Gut Microbiome in Primate Dietary Adaptation.Genes · 2023Article
- High fat diet-induced hyperlipidemia and tissue steatosis in rabbits through modulating ileal microbiota.Applied microbiology and biotechnology · 2022Article
- Human Milk Oligosaccharide Utilization in Intestinal Bifidobacteria Is Governed by Global Transcriptional Regulator NagR.mSystems · 2022Article
- Lactose-reduced infant formula with corn syrup solids and obesity risk among participants in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC).The American journal of clinical nutrition · 2022Article
- Feeding mode influences dynamic gut microbiota signatures and affects susceptibility to anti-CD3 mAb-induced intestinal injury in neonatal mice.American journal of physiology. Gastrointestinal and liver physiology · 2022Article
- The establishment of the gut microbiota in 1-year-aged infants: from birth to family food.European journal of nutrition · 2022Observational
- Adverse Effects of Infant Formula Made with Corn-Syrup Solids on the Development of Eating Behaviors in Hispanic Children.Nutrients · 2022Article
- Integrated Microbiomic and Metabolomic Dynamics of Fermented Corn and Soybean By-Product Mixed Substrate.Frontiers in nutrition · 2022Article
- The Relationship Between Breast Milk Components and the Infant Gut Microbiota.Frontiers in nutrition · 2021Review
- Binary Metabolic Phenotypes and Phenotype Diversity Metrics for the Functional Characterization of Microbial Communities.Frontiers in microbiology · 2021Article
- Metabolic Phenotypes as Potential Biomarkers for Linking Gut Microbiome With Inflammatory Bowel Diseases.Frontiers in molecular biosciences · 2020Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 2 countries.
Funding
Abstract
Infant formula feeding, compared with human milk, has been associated with development of a distinct infant gut microbiome, but no previous study has examined effects of formula with added sugars. This work examined differences in gut microbiota among 91 Hispanic infants who consumed human milk [at breast (BB) vs. pumped in bottle (BP)] and 2 kinds of infant formula [(traditional lactose-based (TF) vs. lactose-reduced with added sugar (ASF)]. At 1 and 6 months, infant stool was collected to characterize gut microbiota. At 6 months, mothers completed 24-hour dietary recalls and questionnaires to determine infant consumption of human milk (BB vs. BP) or formula (TF vs. ASF). Linear regression models were used to determine associations of milk consumption type and microbial features at 6 months. Infants in the formula groups exhibited a significantly more 'mature' microbiome than infants in the human milk groups with the most pronounced differences observed between the ASF vs. BB groups. In the ASF group, we observed reduced log-normalized abundance of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.