Evidence map›Paper›PMID 32887530›Full record

ArticleGut microbes2020

A porcine ligated loop model reveals new insight into the host immune response against

Nicholas M Negretti, Yinyin Ye, Lais M Malavasi, Swechha M Pokharel, Steven Huynh, Susan Noh, Cassidy L Klima, Christopher R Gourley, Claude A Ragle, Santanu Bose and 5 more

Open access · goldAbstract read
In one paragraph

Article in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

  1. Consequences ofMicroorganisms · 2026
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  9. DecreasedPeerJ · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Nicholas M NegrettiSchool of Molecular Biosciences, College of Veterinary Medicine, Washington State University , Pullman, WA, USA.ORCID 0000-0003-1022-8650
Yinyin YeIntegrative Omics, Pacific Northwest National Laboratory , Richland, WA, USA.ORCID 0000-0003-0625-9657
Lais M MalavasiDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University , Pullman, WA, USA.
Swechha M PokharelDepartment of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University , Pullman, WA, USA.
Steven HuynhProduce Safety and Microbiology, United States Department of Agriculture-Agricultural Research Service, Albany, CA, USA.
Susan NohAnimal Disease Research Unit, Agricultural Research Service, United States Department of Agriculture , Pullman, WA, USA.
Cassidy L KlimaFood Safety and Enteric Pathogens Research Unit, National Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture , Ames, IA, USA.
Christopher R GourleySchool of Molecular Biosciences, College of Veterinary Medicine, Washington State University , Pullman, WA, USA.
Claude A RagleDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University , Pullman, WA, USA.
Santanu BoseDepartment of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University , Pullman, WA, USA.
Torey LooftFood Safety and Enteric Pathogens Research Unit, National Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture , Ames, IA, USA.
Craig T ParkerProduce Safety and Microbiology, United States Department of Agriculture-Agricultural Research Service, Albany, CA, USA.ORCID 0000-0002-7719-8882
Geremy ClairIntegrative Omics, Pacific Northwest National Laboratory , Richland, WA, USA.ORCID 0000-0003-0478-8520
Joshua N AdkinsIntegrative Omics, Pacific Northwest National Laboratory , Richland, WA, USA.ORCID 0000-0003-0399-0700
Michael E KonkelSchool of Molecular Biosciences, College of Veterinary Medicine, Washington State University , Pullman, WA, USA.ORCID 0000-0002-8950-0903
Washington State University · USAgricultural Research Service · USPacific Northwest National Laboratory · US

Funding

Infectious Diseases and Microbial Immunology Training ProgramT32AI007025 · NIAID · WASHINGTON STATE UNIVERSITY · PI Thomas H KAWULA, M KARIUKI NJENGA · 1985 to 2026
$7.4M
Consortia for High-Throughput-Enabled Structural Biology Partnerships (U01)U01GM094623 · NIGMS · BATTELLE PACIFIC NORTHWEST LABORATORIES · PI ADKINS, JOSHUA N. · 2010 to 2014
$5.2M
Molecular and cellular mechanism regulating innate immunity and inflammation during pattern recognition receptor activation and respiratory virus infectionR01AI083387 · NIAID · WASHINGTON STATE UNIVERSITY · PI BOSE, SANTANU · 2010 to 2021
$3.1M
Molecular and Cellular Dissection of Campylobacter Jejuni Effector Protein FunctionR01AI125356 · NIAID · WASHINGTON STATE UNIVERSITY · PI KONKEL, MICHAEL E · 2016 to 2020
$1.9M
Dynamics of Campylobacter jejuni and host responses in the porcine intestinal-loop infection modelR21AI124144 · NIAID · WASHINGTON STATE UNIVERSITY · PI KONKEL, MICHAEL E · 2017 to 2018
$420k
NIAID NIH HHS R01 AI083387NIAID NIH HHS R01 AI125356NIAID NIH HHS R21 AI124144NIAID NIH HHS T32 AI007025NIGMS NIH HHS U01 GM094623
6 · The paper itself

Abstract

The symptoms of infectious diarrheal disease are mediated by a combination of a pathogen's virulence factors and the host immune system.

Indexed as

AnimalsCampylobacter InfectionsCampylobacter jejuniCell LineCytokinesDisease Models, AnimalEpithelial CellsGastrointestinal MicrobiomeInflammationIntestinal MucosaIntestine, SmallMacrophagesNeutrophilsProteomeSwineSwine, MiniatureCytokinesProteomeVirulence FactorsDisease modelinnate immunityintestinal diseasepathogenesisproteomics

Identifiers

PMID32887530
PMCPMC7524355
OpenAlexW3083557098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.