Evidence map›Paper›PMID 32887413›Full record

ArticleBiomolecules2020

Targeting MHC Regulation Using Polycyclic Polyprenylated Acylphloroglucinols Isolated from

Chloé Coste, Nathalie Gérard, Chau Phi Dinh, Antoine Bruguière, Caroline Rouger, Sow Tein Leong, Khalijah Awang, Pascal Richomme, Séverine Derbré, Béatrice Charreau

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. CBP/p300, a promising therapeutic target for prostate cancer.Journal of translational medicine · 2025
    Review
  2. Article
  3. Molecular and functional characterization of an evolutionarily conserved CREB-binding protein in the Lymnaea CNS.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022
    Article
  4. Advances in Endothelial Cell Biology: From Knowledge to Control.International journal of molecular sciences · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Chloé CosteUniversité de Nantes, CHU Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, F-44000 Nantes, France.
Nathalie GérardUniversité de Nantes, CHU Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, F-44000 Nantes, France.ORCID 0000-0002-8818-1736
Chau Phi DinhSONAS, EA921, University of Angers, SFR QUASAV, Faculty of Health Sciences, Department of Pharmacy, CEDEX 01, 49045 Angers, France.ORCID 0000-0002-3683-3472
Antoine BruguièreSONAS, EA921, University of Angers, SFR QUASAV, Faculty of Health Sciences, Department of Pharmacy, CEDEX 01, 49045 Angers, France.
Caroline RougerSONAS, EA921, University of Angers, SFR QUASAV, Faculty of Health Sciences, Department of Pharmacy, CEDEX 01, 49045 Angers, France.ORCID 0000-0002-6442-6567
Sow Tein LeongDepartment of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia.ORCID 0000-0003-0974-7621
Khalijah AwangDepartment of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia.
Pascal RichommeSONAS, EA921, University of Angers, SFR QUASAV, Faculty of Health Sciences, Department of Pharmacy, CEDEX 01, 49045 Angers, France.
Séverine DerbréSONAS, EA921, University of Angers, SFR QUASAV, Faculty of Health Sciences, Department of Pharmacy, CEDEX 01, 49045 Angers, France.ORCID 0000-0002-3953-5745
Béatrice CharreauUniversité de Nantes, CHU Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, F-44000 Nantes, France.ORCID 0000-0001-5870-4615
Université d'Angers · FRInserm · FRUniversity of Malaya · MY

Funding

Association Vaincre la Mucoviscidose RF20190502487Conseil Régional des Pays de la Loire HYPROTECInstitut de recherche en santé respiratoire des Pays de la Loire CYTOPMinistère de l'Enseignement supérieur, de la Recherche et de l'Innovation PANASIAMinistère de l'Europe et des Affaires étrangères travel grants
6 · The paper itself

Abstract

Modulation of major histocompatibility complex (MHC) expression using drugs has been proposed to control immunity. Phytochemical investigations on

Indexed as

AcylationATP Binding Cassette Transporter, Subfamily B, Member 2BenzophenonesDown-RegulationEndothelial CellsGarciniaGATA2 Transcription FactorHumansInterferon-gammaMajor Histocompatibility ComplexMembrane Transport ProteinsMolecular Docking SimulationNuclear Proteinsp300-CBP Transcription FactorsPhloroglucinolPolycyclic CompoundsATP Binding Cassette Transporter, Subfamily B, Member 2BenzophenonesgarcinolGATA2 protein, humanGATA2 Transcription Factorguttiferone FIFNG protein, humanInterferon-gammaMembrane Transport ProteinsMHC class II transactivator proteinNuclear Proteinsp300-CBP Transcription FactorsPhloroglucinolPolycyclic CompoundsSTAT1 protein, humanSTAT1 Transcription FactorTAP1 protein, humantapasinTerpenesTrans-ActivatorsxanthochymolClusiaceaeendotheliumGarcinia bancanaguttiferone Fguttiferone Jhistone acetyltransferaseHLA-Emajor histocompatibility complexpolycyclic polyprenylated acylphloroglucinolsxanthochymol

Identifiers

PMID32887413
PMCPMC7563419
OpenAlexW3082896894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.