ReviewNutrients2020
A Review of the Potential Interaction of Selenium and Iodine on Placental and Child Health.
Review in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 21 citations in OpenAlex.
- Impact of lipid-based nutritional supplementation on cardio metabolic risk factors in underweight pre-eclamptic primigravidas: A randomized controlled trial.BMC pregnancy and childbirth · 2026Trial
- A Multicountry Analysis of Maternal Selenium Status in Pregnancy and Lactation and Infant Birth Outcomes: Findings from the Women First Maternal Preconception Study.The Journal of nutrition · 2026Trial
- Effect of Lipid-Based Multiple Micronutrients Supplementation in Underweight Primigravida Pre-Eclamptic Women on Maternal and Pregnancy Outcomes: Randomized Clinical Trial.Medicina (Kaunas, Lithuania) · 2022Trial
- Association Between Dietary Phytochemical Index and Neonatal Thyroid Function.Journal of pregnancy · 2024Article
- Effects of Gestational Diabetes Mellitus and Selenium Deficiency on the Offspring Growth and Blood Glucose Mechanisms of C57BL/6J Mice.Nutrients · 2023Article
- Selenium status in term neonates, according to birth weight and gestational age, in relation to maternal hypertensive pathology.Frontiers in pediatrics · 2023Article
- Iodine nutrition level and thyroid function in pregnant women in the Yongchuan district of Chongqing.Journal of clinical and translational research · 2022Article
- Associations between Maternal Selenium Status and Cord Serum Vitamin D Levels: A Birth Cohort Study in Wuhan, China.Nutrients · 2022Article
- Immunonutrients involved in the regulation of the inflammatory and oxidative processes: implication for gamete competence.Journal of assisted reproduction and genetics · 2022Review
- Vaccines, Microbiota and Immunonutrition: Food for Thought.Vaccines · 2022Review
- Nutritional Status of Selenium and Its Association with Diet and Indoor Air Pollution among Pregnant Women in a Rural Area of Northern China.International journal of environmental research and public health · 2021Article
- Fetal Programming Is Deeply Related to Maternal Selenium Status and Oxidative Balance; Experimental Offspring Health Repercussions.Nutrients · 2021Review
- Neonatal Selenoenzyme Expression Is Variably Susceptible to Duration of Maternal Selenium Deficiency.Antioxidants (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A healthy pregnancy is important for the growth and development of a baby. An adverse pregnancy outcome is associated with increased chronic disease risk for the mother and offspring. An optimal diet both before and during pregnancy is essential to support the health of the mother and offspring. A key mediator of the effect of maternal nutrition factors on pregnancy outcomes is the placenta. Complicated pregnancies are characterized by increased oxidative stress in the placenta. Selenium and iodine are micronutrients that are involved in oxidative stress in placental cells. To date, there has been no comprehensive review investigating the potential synergistic effect of iodine and selenium in the placenta and how maternal deficiencies may be associated with increased oxidative stress and hence adverse pregnancy outcomes. We undertook a hypothesis-generating review on selenium and iodine, to look at how they may relate to pregnancy complications through oxidative stress. We propose how they may work together to impact pregnancy and placental health and explore how deficiencies in these micronutrients during pregnancy may impact the future health of offspring.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.