Evidence map›Paper›PMID 32887371›Full record

ArticleBiomolecules2020

8-Deoxy-Rifamycin Derivatives from

Feng Ye, Yanrong Shi, Shengliang Zhao, Zhiying Li, Haoxin Wang, Chunhua Lu, Yuemao Shen

Abstract read
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Looking Back toAntibiotics (Basel, Switzerland) · 2021
    Review
  6. Review
  7. Rifamycin W Analogues fromBiomolecules · 2021
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Feng YeKey Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, No. 44 West Wenhua Road, Jinan 250012, China.
Yanrong ShiKey Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, No. 44 West Wenhua Road, Jinan 250012, China.ORCID 0000-0002-3738-2060
Shengliang ZhaoKey Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, No. 44 West Wenhua Road, Jinan 250012, China.
Zhiying LiKey Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, No. 44 West Wenhua Road, Jinan 250012, China.
Haoxin WangState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Chunhua LuKey Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, No. 44 West Wenhua Road, Jinan 250012, China.
Yuemao ShenKey Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, No. 44 West Wenhua Road, Jinan 250012, China.ORCID 0000-0002-3881-0135

Funding

National Natural Science Foundation of China 81673317, 81602979, 81530091Program for Changjiang Scholars and Innovative Research Team in University IRT_17R68the Open Funding Project of State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University MMLKF17-09
6 · The paper itself

Abstract

Proansamycin X, a hypothetical earliest macrocyclic precursor in the biosynthesis of rifamycin, had never been isolated and identified. According to bioinformatics analysis, it was proposed that RifT (a putative NADH-dependent dehydrogenase) may be a candidate target responsible for the dehydrogenation of proansamycin X. In this study, the mutant strain

Indexed as

AmycolatopsisAnti-Bacterial AgentsCell Line, TumorCell ProliferationGene Knockout TechniquesHumansMagnetic Resonance SpectroscopyMicrobial Sensitivity TestsOxidoreductasesPolyketidesRifamycinsSpectrometry, Mass, Electrospray IonizationStaphylococcus aureusAnti-Bacterial AgentsOxidoreductasesPolyketidesRifamycinsAmycolatopsis mediterranei S699dehydrogenationN-glycoside rifamycinproansamycin Xrifamycin

Identifiers

PMID32887371
PMCPMC7563148

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.