ArticleFoods (Basel, Switzerland)2020
The Impact of Germination on Sorghum Nutraceutical Properties.
Article in Foods (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
19 citing papers in PubMed, 50 citations in OpenAlex.
- Germination-Driven Modulation of Phenolic Compounds in Sorghum: Bioactivity and Gene Expression.Foods (Basel, Switzerland) · 2026Review
- The Germination Paradox in Sorghum: A Review.Foods (Basel, Switzerland) · 2026Review
- Article
- Health-Promoting Properties of Sorghum Bioactive Compounds-A Comprehensive Bibliometric Analysis.Nutrients · 2025Review
- Phenolic Composition, Functional Groups, In Vitro Bioactivities, and Techno-Functional Properties of Whole and Composite Bioprocessed Flours From Cowpea, Sorghum and Orange-Fleshed Sweet Potato.Journal of food science · 2025Article
- Optimization of the germination time of proso and foxtail millets to enhance the bioactive properties, antioxidant activity, and enzymatic power and reduce antinutritional factor.Current research in food science · 2025Article
- How to assess antioxidant activity? Advances, limitations, and applications of in vitro, in vivo, and ex vivo approaches.Food production, processing and nutrition · 2025Review
- Functional, nutritional, and sensorial evaluation of sorghum-based beverages produced by single- and two-stage acid, α-amylase enzyme, and germination treatments.Food science & nutrition · 2024Article
- Utilization of Germinated Seeds as Functional Food Ingredients: Optimization of Nutrient Composition and Antioxidant Activity Evolution Based on the Germination Characteristics of Chinese Chestnut (Foods (Basel, Switzerland) · 2024Article
- Complementary nutritional and health promoting constituents in germinated and probiotic fermented flours from cowpea, sorghum and orange fleshed sweet potato.Scientific reports · 2024Article
- Effect of fermentation, malting and ultrasonication on sorghum, mopane worm andFrontiers in nutrition · 2024Article
- Unlocking the Potential of Sprouted Cereals, Pseudocereals, and Pulses in Combating Malnutrition.Foods (Basel, Switzerland) · 2023Review
- Modification on phenolic profiles and enhancement of antioxidant activity of proso millets during germination.Food chemistry: X · 2023Article
- Genome-Wide Association Study of Seed Morphology Traits in Senegalese Sorghum Cultivars.Plants (Basel, Switzerland) · 2023Article
- Sourdough Fermentation Improves the Antioxidant, Antihypertensive, and Anti-Inflammatory Properties ofInternational journal of molecular sciences · 2023Article
- Bio-Functional Activities of Tuscan Bee Pollen.Antioxidants (Basel, Switzerland) · 2023Article
- Effects of Exogenous Caffeic Acid, L-Phenylalanine and NaCl Treatments on Main Active Components Content andFoods (Basel, Switzerland) · 2022Article
- Cereals as a Source of Bioactive Compounds with Anti-Hypertensive Activity and Their Intake in Times of COVID-19.Foods (Basel, Switzerland) · 2022Review
- Germinated Buckwheat: Effects of Dehulling on Phenolics Profile and Antioxidant Activity of Buckwheat Seeds.Foods (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Sorghum is a gluten-free cereal representing a staple food in many countries of Africa, where germination is traditionally used for the preparation of several sorghum-based products. This study focused on the effect of germination on total phenolic content, in vitro and ex vivo antioxidant activity, and antihypertensive action of sorghum from Togo. Total phenolic content was estimated as Folin-Ciocalteu reducing capacity, while antioxidant activities were assessed using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and Ferric Reducing Antioxidant Power (FRAP) in vitro tests and ex vivo by the cellular antioxidant activity (CAA) assay on human erythrocytes. The antihypertensive effect of germinated and non-germinated sorghum peptides fraction was evaluated as angiotensin-converting enzyme (ACE) inhibitory activity. Despite our findings demonstrated no impact of germination on the total phenolic content, non-germinated sorghum showed significantly higher in vitro antioxidant activities than the germinated one; further, non-germinated sorghum displayed significantly higher ACE inhibition than germinated sorghum that, instead, at lower doses, exhibited better erythrocytes protection from peroxyl radicals. In conclusion, the germination process negatively impacted the in vitro antioxidant activity and the antihypertensive effect of sorghum while improved erythrocytes protection. This study evidenced better nutraceutical potential of non-germinated sorghum that, besides good antioxidant activity, represents an important source of ACE-inhibitory peptides. However, the germination process might have positively impacted the profile of bioactive compounds involved in the protection of human erythrocytes from oxidative damage.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.