ArticleThe Journal of physiology2020
Locomotor muscle group III/IV afferents constrain stroke volume and contribute to exercise intolerance in human heart failure.
Article in The Journal of physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Effect of opioids for breathlessness in heart failure: a systematic review and meta-analysis.Heart (British Cardiac Society) · 2023Pooled it
- Application of Inspiratory Muscle Training to Improve Physical Tolerance in Older Patients with Ischemic Heart Failure.International journal of environmental research and public health · 2021Trial
- Opioid Use for Dyspnoea in Advanced Heart Failure.Current heart failure reports · 2026Review
- Associations of thigh muscle thickness with cardiorespiratory fitness and ventilatory efficiency in male soccer athletes.Scientific reports · 2026Article
- Protein kinase C epsilon contributes to chronic mechanoreflex sensitization in rats with heart failure.The Journal of physiology · 2025Article
- Novel role for purinergic 2× subtype 4 (P2X4) receptors in the exercise pressor reflex and mechanoreflex: Effect of heart failure.Autonomic neuroscience : basic & clinical · 2025Article
- Dissecting the exercise pressor reflex in heart failure: A multi-step failure.Autonomic neuroscience : basic & clinical · 2025Review
- Thoracic load carriage impairs the acute physiological response to hypoxia in healthy males.Physiological reports · 2025Article
- Influence of blood lactate variations and passive exercise on cardiac responses.Journal of physical therapy science · 2024Article
- Consequences of group III/IV afferent feedback and respiratory muscle work on exercise tolerance in heart failure with reduced ejection fraction.Experimental physiology · 2023Review
- Article
- Novel mechanosensory role for acid sensing ion channel subtype 1a in evoking the exercise pressor reflex in rats with heart failure.The Journal of physiology · 2022Article
- Influence of locomotor muscle group III/IV afferents on cardiovascular and ventilatory responses in human heart failure during submaximal exercise.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- Sex and age interaction in fundamental circulatory volumetric variables at peak working capacity.Biology of sex differences · 2022Article
- Regulation of the microvasculature during small muscle mass exercise in chronic obstructive pulmonary disease vs. chronic heart failure.Frontiers in physiology · 2022Article
- Skeletal Muscle Contractile Function in Heart Failure With Reduced Ejection Fraction-A Focus on Nitric Oxide.Frontiers in physiology · 2022Review
- Thromboxane APhysiological reports · 2021Article
- Exaggerated sympathetic and cardiovascular responses to dynamic mechanoreflex activation in rats with heart failure: Role of endoperoxide 4 and thromboxane AAutonomic neuroscience : basic & clinical · 2021Article
- Unraveling the Role of Respiratory Muscle Metaboloreceptors under Inspiratory Training in Patients with Heart Failure.International journal of environmental research and public health · 2021Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
key pointsHeart failure patients with reduced ejection fraction (HFrEF) exhibit severe limitations in exercise capacity ( ABSTRACT: To better understand the underlying mechanisms contributing to exercise limitation in heart failure with reduced ejection fraction (HFrEF), we investigated the influence of locomotor muscle group III/IV afferent inhibition via lumbar intrathecal fentanyl on peak exercise capacity (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.