ArticleBioprocess and biosystems engineering2021
Efficacy of red light for enhanced cell disruption and fluorescence intensity of phycocyanin.
Article in Bioprocess and biosystems engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 24 citations in OpenAlex.
- High-Purity Phycocyanin Production from Cyanobacteria Using a Biorefinery Approach: Life Cycle Assessment and Comparative Process Benchmarking.Microorganisms · 2026Article
- Phycobilins Versatile Pigments with Wide-Ranging Applications: Exploring Their Uses, Biological Activities, Extraction Methods and Future Perspectives.Marine drugs · 2025Review
- Cyanobacterial Phycocyanin-Based Electrochemical Biosensor for the Detection of the Free Radical Hydrogen Peroxide.Applied biochemistry and biotechnology · 2024Article
- Article
- Laser Treatment Increases the Antimicrobial Efficacy of Cyanobacterial Extracts againstInternational journal of environmental research and public health · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, red LED and urea used as light and nitrogen sources, respectively, for the cultivation of Spirulina to enhance the fluorescence property and purity of phycocyanin. Besides, there is a high concentration of phycocyanin leached out from red light (RL) grown cells than white light (WL) without cell disruption. This type of cultivation reduces the complexity of extraction methods and cost of the downstream process. The fluorescence intensity of C-PC enhanced while using red LEDs and purity ratio improved by single-step cation exchange chromatography. Phycocyanin from red-light-exposed culture exhibited pronounced antibacterial activity against bacteria. The hydrogen peroxide scavenging activity of C-PC (93.7%) is higher than the WL cultures (88.8%). Phycocyanin from RL culture exhibited a strong antiproliferative activity (64.1%) against HeLa cancer cell line. The present study aims to analyze the influence of red light and urea on enhancing the phycocyanin production.
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Registered trials
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