ArticleCancer2020
Association of malnutrition with geriatric assessment impairments and health-related quality of life among older adults with gastrointestinal malignancies.
Article in Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- The bidirectional association of malnutrition with depression and anxiety in patients with cancer: a systematic review and meta-analysis of evidence.Aging clinical and experimental research · 2025Pooled it
- Falls among geriatric cancer patients: a systematic review and meta-analysis of prevalence and risk across cancer types.BMC geriatrics · 2025Pooled it
- Nutritional Impairment and Quality of Life Trajectories Among Older Adults With Advanced Cancer.Journal of the American Geriatrics Society · 2025Trial
- Investigating demographic and geographic disparities in malnutrition and gastrointestinal cancer mortality among older adults in the United States: A comprehensive longitudinal Centers for Disease Control and Prevention WONDER analysis 1999-2020.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026Article
- A patient-mediated implementation strategy to improve nutrition care delivery for esophageal and gastric cancer: a study protocol for a pilot randomized controlled trial.Journal of health, population, and nutrition · 2025Article
- Nutritional Challenges in Older Cancer Patients: A Narrative Review of Assessment Tools and Management Strategies.Nutrients · 2025Review
- Multimodal Prehabilitation in Major Abdominal Surgery-Rationale, Modalities, Results and Limitations.Medicina (Kaunas, Lithuania) · 2025Review
- Retrospective Analysis of the Impact of a Dietitian and the Canadian Nutrition Screening Tool in a Geriatric Oncology Clinic.Nutrients · 2025Article
- Prevalence and incidence of falls in older adults with cancer: a systematic review with meta-analysis.Journal of cancer survivorship : research and practice · 2025Review
- Observational
- The association between social vulnerability index and survival in older adults with gastrointestinal cancers - The CARE Registry.Journal of geriatric oncology · 2025Article
- Article
- Association between GLIM-diagnosed malnutrition and quality of life in older patients with cancer.The journal of nutrition, health & aging · 2024Observational
- Geriatric Assessment Impairment Profiles and Mortality in Older Adults With Gastrointestinal Cancers: Latent Class Analysis of the CARE Registry.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Longitudinal changes in patient-reported cognitive complaints among older adults with gastrointestinal malignancies - results from the Cancer and Aging Resilience Evaluation (CARE) Registry.Journal of cancer survivorship : research and practice · 2024Article
- Article
- Article
- Effects of Potentially Inappropriate Medications in Older Patients with Gastrointestinal System Cancer.Medeniyet medical journal · 2023Article
- Bioimpedentiometry parameters used as indicators of frailty and malnutrition: association between G8 score and Phase angle (PHA) in elderly cancer patients.Aging clinical and experimental research · 2023Article
- Predicting Risk of Severe Toxicity and Early Death in Older Adult Patients Treated with Chemotherapy.Cancers · 2023Article
Corrections and comments
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
Abstract
backgroundA majority of older adults with cancer develop malnutrition; however, the implications of malnutrition among this vulnerable population are poorly understood. The goal of this study was to quantify the prevalence of nutrition related-symptoms and malnutrition among older adults with gastrointestinal (GI) malignancies and the association of malnutrition with geriatric assessment (GA) impairment, health-related quality of life (HRQoL), and health care utilization.
methodsWe performed a cross-sectional study of older adults (≥60 years) who were referred to the GI Oncology clinic at the University of Alabama at Birmingham. Participants underwent the Cancer & Aging Resilience Evaluation survey that includes the abbreviated Patient-Generated Subjective Global Assessment of nutrition. Nutrition scores were dichotomized into normal (0-5) and malnourished (≥6), and multivariate analyses adjusted for demographics, cancer type, and cancer stage were used to examine associations with GA impairment, HRQoL, and health care utilization.
resultsA total of 336 participants were included (men, 56.8%; women, 43.2%), with a mean age of 70 years (standard deviation, ±7.2 years) and colorectal cancer (33.6%) and pancreatic cancer (24.4%) being the most common diagnoses. Overall, 52.1% of participants were identified as malnourished. Malnutrition was associated with a higher prevalence of several GA impairments, including 1 or more falls (adjusted odds ratio [aOR], 2.1), instrumental activities of daily living impairment (aOR, 4.1), and frailty (aOR, 8.2). Malnutrition was also associated with impaired HRQoL domains; both physical (aOR, 8.7) and mental (aOR, 5.0), and prior hospitalizations (aOR, 2.2).
conclusionWe found a high prevalence of malnutrition among older adults with GI malignancies that was associated with increased GA impairments, reduced HRQoL, and increased health care utilization.
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