Evidence map›Paper›PMID 32885739›Full record

ArticleUltrasonic imaging

Deep Learning for Carotid Plaque Segmentation using a Dilated U-Net Architecture.

Nirvedh H Meshram, Carol C Mitchell, Stephanie Wilbrand, Robert J Dempsey, Tomy Varghese

Abstract read
In one paragraph

Article in Ultrasonic imaging. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Mask R-CNN-based carotid plaque localization in ultrasound images.Journal of medical imaging (Bellingham, Wash.) · 2026
    Article
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  4. Review
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  14. Application and prospects of AI-based radiomics in ultrasound diagnosis.Visual computing for industry, biomedicine, and art · 2023
    Review
  15. Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nirvedh H MeshramDepartment of Biomedical Engineering, Columbia University, New York, NY, USA.ORCID 0000-0003-4005-9798
Carol C MitchellDepartment of Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.
Stephanie WilbrandDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.
Robert J DempseyDepartment of Neurological Surgery, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.
Tomy VargheseDepartment of Medical Physics, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.ORCID 0000-0003-3299-9130

Funding

Early Detection of Vascular Dysfunction Using Biomarkers from Lagrangian Carotid Strain ImagingR01HL147866 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI VARGHESE, TOMY · 2020 to 2023
$2.9M
Real-time Ultrasonic Monitoring of Tumor AblationR01CA112192 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI VARGHESE, TOMY · 2007 to 2017
$2.6M
Structural Stability of Carotid Plaque and SymptomatologyR01NS064034 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI DEMPSEY, ROBERT J · 2010 to 2014
$1.5M
NCI NIH HHS R01 CA112192NHLBI NIH HHS R01 HL147866NINDS NIH HHS R01 NS064034
6 · The paper itself

Abstract

Carotid plaque segmentation in ultrasound longitudinal B-mode images using deep learning is presented in this work. We report on 101 severely stenotic carotid plaque patients. A standard U-Net is compared with a dilated U-Net architecture in which the dilated convolution layers were used in the bottleneck. Both a fully automatic and a semi-automatic approach with a bounding box was implemented. The performance degradation in plaque segmentation due to errors in the bounding box is quantified. We found that the bounding box significantly improved the performance of the networks with U-Net Dice coefficients of 0.48 for automatic and 0.83 for semi-automatic segmentation of plaque. Similar results were also obtained for the dilated U-Net with Dice coefficients of 0.55 for automatic and 0.84 for semi-automatic when compared to manual segmentations of the same plaque by an experienced sonographer. A 5% error in the bounding box in both dimensions reduced the Dice coefficient to 0.79 and 0.80 for U-Net and dilated U-Net respectively.

Indexed as

Deep LearningCarotid ArteriesCarotid StenosisHumansImage Interpretation, Computer-AssistedPlaque, AtheroscleroticUltrasonographycarotid plaquedeep learningsegmentation

Identifiers

PMID32885739
PMCPMC8045553

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.