Evidence map›Paper›PMID 32885328›Full record

SynthesisTechniques in coloproctology2021

Assessment of intraoperative use of indocyanine green fluorescence imaging on the incidence of anastomotic leakage after rectal cancer surgery: a PRISMA-compliant systematic review and meta-analysis.

M Song, J Liu, D Xia, H Yao, G Tian, X Chen, Y Liu, Y Jiang, Z Li

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Techniques in coloproctology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 4 pooled it
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 4 syntheses or guidelines pooled it, 37 citations in OpenAlex.

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  14. Fluorescent ICG angiography in laparoscopic rectal resection - a randomized controlled trial. Preliminary report.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

M SongDepartment of Laboratory Medicine, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
J LiuDepartment of Laboratory Medicine, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
D XiaDepartment of Gastrointestinal Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China.
H YaoDepartment of Gastrointestinal Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China.
G TianDepartment of Laboratory Medicine, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
X ChenDepartment of Gastrointestinal Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China.
Y LiuDepartment of Gastrointestinal Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China.
Y JiangDepartment of Gastrointestinal Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China.
Z LiDepartment of Gastrointestinal Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China. lizonglin85@163.com.ORCID http://orcid.org/0000-0002-5240-9858
Affiliated Hospital of Southwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe current data on the intraoperative use of indocyanine green (ICG) fluorescence imaging to reduce the anastomotic leak (AL) rate in rectal cancer surgery remain controversial. The aim of this systematic review and meta-analysis was to evaluate the efficacy of ICG fluorescence imaging in decreasing the AL rate after rectal cancer surgery.

methodsStudies comparing ICG fluorescence imaging with standard care in patients with rectal cancer were systematically searched from PubMed, Embase, Web of Science and Cochrane Library through January 2020. The current meta-analysis was performed according to the preferred reporting items for systematic review and meta-analysis guidelines. A pooled analysis was performed for the available data regarding the baseline features, AL rate and other surgical outcomes. RevMan version 5.3 software was used for the present meta-analysis.

resultsNine studies with a total of 2088 patients with rectal cancer (926 in the ICG group and 1162 in the control group) were included in the present study. In the pooled analysis, the available patient and tumour-related baseline data were all comparable and without significant heterogeneity. In the present pooled analysis, the AL rate in the ICG group was significantly lower (OR 0.34; 95% CI 0.22-0.52; p < 0.0001) than that in the control group. Additionally, intraoperative use of ICG was associated with a decreased overall complication rate (OR 0.57; 95% CI 0.42-0.78; p = 0.0003) and reduced reoperation rate (OR 0.26; 95% CI 0.08-0.86; p = 0.03) in patients who had rectal cancer surgery.

conclusionsThe present study demonstrated the superiority of the intraoperative use of ICG in reducing the AL rate. However, considering the limitations of the included studies, more high-quality prospective studies and randomized controlled trials are needed.

Indexed as

Indocyanine GreenRectal NeoplasmsAnastomotic LeakHumansIncidenceOptical ImagingProspective StudiesIndocyanine GreenAnastomotic leakFluorescenceIndocyanine greenMeta-analysisRectal neoplasms

Identifiers

PMID32885328
OpenAlexW3083380263

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.