Evidence map›Paper›PMID 32885223›Full record

ArticleEJHaem2020

Prognostic plasma biomarkers of early complications and graft-versus-host disease in patients undergoing allogeneic hematopoietic stem cell transplantation.

Balaji Balakrishnan, Raveen Stephen Stallon Illangeswaran, Bharathi M Rajamani, Aswin Anand Pai, Infencia Xavier Raj, Daniel Zechariah Paul, Kavitha Lakshmi, Thenmozhi Mani, Ezhilpavai Mohanan, Uday Kulkarni and 9 more

Open access · diamondAbstract read
In one paragraph

Article in EJHaem, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 2 countries.

Balaji BalakrishnanDepartment of Haematology, Christian Medical College, Vellore, India.
Raveen Stephen Stallon IllangeswaranDepartment of Haematology, Christian Medical College, Vellore, India.
Bharathi M RajamaniDepartment of Haematology, Christian Medical College, Vellore, India.
Aswin Anand PaiDepartment of Haematology, Christian Medical College, Vellore, India.
Infencia Xavier RajDepartment of Haematology, Christian Medical College, Vellore, India.
Daniel Zechariah PaulDepartment of Haematology, Christian Medical College, Vellore, India.
Kavitha LakshmiDepartment of Haematology, Christian Medical College, Vellore, India.
Thenmozhi ManiDepartment of Biostatistics, Christian Medical College, Vellore, India.
Ezhilpavai MohananDepartment of Haematology, Christian Medical College, Vellore, India.
Uday KulkarniDepartment of Haematology, Christian Medical College, Vellore, India.
Anup Joseph DevasiaDepartment of Haematology, Christian Medical College, Vellore, India.
N A FouziaDepartment of Haematology, Christian Medical College, Vellore, India.
Anu KorulaDepartment of Haematology, Christian Medical College, Vellore, India.
Aby AbrahamDepartment of Haematology, Christian Medical College, Vellore, India.
Alok SrivastavaDepartment of Haematology, Christian Medical College, Vellore, India.ORCID https://orcid.org/0000-0001-5032-5020
Vikram MathewsDepartment of Haematology, Christian Medical College, Vellore, India.
Sophie PaczesnyIndiana University School of Medicine, Indianapolis, Indiana, USA.ORCID https://orcid.org/0000-0001-5571-2775
Biju GeorgeDepartment of Haematology, Christian Medical College, Vellore, India.
Poonkuzhali BalasubramanianDepartment of Haematology, Christian Medical College, Vellore, India.ORCID https://orcid.org/0000-0002-9443-439X
Christian Medical College, Vellore · INIndiana University School of Medicine

Funding

DBT-Wellcome Trust India Alliance IA/CPHE/17/1/503351DBT-Wellcome Trust India Alliance IA/CPHS/18/1/503930DBT-Wellcome Trust India Alliance IA/S/15/1/501842Wellcome Trust
6 · The paper itself

Abstract

Early complications post hematopoietic stem cell transplantation (HSCT) such as sinusoidal obstruction syndrome (SOS) and graft versus host disease (GVHD) can be life threatening. Although several biomarkers have been identified to correlate with these complications and their response to treatment, these are yet to be used in clinical practice. Here, we evaluated circulating endothelial cells (CECs) (n = 26) and plasma biomarkers (ST2, REG3

Indexed as

GVHDHSC transplantationprognostic

Identifiers

PMID32885223
PMCPMC7116009
OpenAlexW3036546666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.