Evidence map›Paper›PMID 32885147›Full record

ReviewHemaSphere2020

A Pathophysiological Perspective on the SARS-CoV-2 Coagulopathy.

Nuray Kusadasi, Maaike Sikma, Albert Huisman, Jan Westerink, Coen Maas, Roger Schutgens

Open access · goldAbstract readReview
In one paragraph

Review in HemaSphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. The role of extracellular histones in COVID-19.Journal of internal medicine · 2023
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nuray KusadasiDepartment of Intensive Care Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
Maaike SikmaDepartment of Intensive Care Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
Albert HuismanCentral Diagnostic Laboratory, University Medical Center Utrecht, Utrecht, The Netherlands.
Jan WesterinkDepartment of Vascular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
Coen MaasCentral Diagnostic Laboratory, University Medical Center Utrecht, Utrecht, The Netherlands.
Roger SchutgensVan Creveldkliniek, Benign Hematology Center, University Medical Center Utrecht, Utrecht, The Netherlands.
University Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent evidence is focusing on the presence of a hypercoagulable state with development of both venous and arterial thromboembolic complications in patients infected with SARS-CoV-2. The ongoing activation of coagulation related to the severity of the illness is further characterized by thrombotic microangiopathy and endotheliitis. These microangiopathic changes cannot be classified as classical disseminated intravascular coagulation (DIC). In this short review we describe the interaction between coagulation and inflammation with focus on the possible mechanisms that might be involved in SARS-CoV-2 infection associated coagulopathy in the critically ill.

Identifiers

PMID32885147
PMCPMC7430228
OpenAlexW3048657764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.