ArticleEnvironmental epidemiology (Philadelphia, Pa.)2019
Early-life exposure to traffic-related air pollution and child anthropometry.
Article in Environmental epidemiology (Philadelphia, Pa.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Ambient air pollution and childhood obesity from infancy to late childhood: An individual participant data meta-analysis of 10 European birth cohorts.Environment international · 2025Pooled it
- POLE Deficiency Exacerbates Diesel Engine Exhaust-Induced Genomic Instability and Malignant Transformation of Bronchial Epithelial Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Examining the Link between Air Quality (PM, SOJournal of clinical medicine · 2024Review
- Early-life exposure to residential black carbon and childhood cardiometabolic health.Environmental research · 2023Article
- Fine particulate matter (PMThe Science of the total environment · 2023Article
- Early-life residential green spaces and traffic exposure in association with young adult body composition: a longitudinal birth cohort study of twins.Environmental health : a global access science source · 2023Article
- Prenatal exposure to ambient air pollution and traffic and indicators of adiposity in early childhood: the Healthy Start study.International journal of obesity (2005) · 2022Article
- Air pollution and childhood obesity.Clinical and experimental pediatrics · 2020Article
- Adolescent follow-up in the Health Outcomes and Measures of the Environment (HOME) Study: cohort profile.BMJ open · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundEarly-life exposure to traffic-related air pollution may decrease fetal growth and increase childhood obesity risk. Our objective was to evaluate the relationship of early-life exposure to traffic-related air pollution with birthweight in term newborns and obesity at age 7-8 years in two prospective birth cohorts in Cincinnati, OH (the Health Outcomes and Measures of the Environment (HOME) Study and Cincinnati Childhood Allergy and Air Pollution Study (CCAAPS)).
methodsWe estimated elemental carbon attributable to traffic (ECAT) exposure at residential addresses during pregnancy with a validated land use regression model. We assessed birthweight among term infants using birth records or parent report (HOME Study n= 333 and CCAAPS n=590). We measured children's weight and height at 7-8 years, and calculated age- and sex-specific BMI z-scores (HOME Study n= 198 and CCAAPS n=459). Using multivariable linear regression, we estimated the difference in term birthweight and BMI z-score per interquartile range (IQR) increase in ECAT concentrations in each cohort separately and in the pooled sample.
resultsIn adjusted models, ECAT exposure was not associated with lower birthweight (pooled sample β: 30g; 95% CI: -6, 66), or with higher BMI z-score (pooled sample β: -0.04; 95% CI: -0.15, 0.08). Infant sex modified the association between ECAT and birthweight (p=0.05). Among male newborns, higher ECAT concentrations were associated with higher birthweight (β: 61g; 95% CI: 9, 113), but we observed no association among female newborns (β: -9g; 95% CI: -58, 41).
conclusionsIn contrast to some prior studies, early-life traffic-related air pollution exposure was not associated with lower birthweight or increased childhood adiposity in these two cohorts.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.