Evidence map›Paper›PMID 32884966›Full record

ArticleChild neurology open

Brain Characteristics Noted Prior to and Following Cranial Orthotic Treatment.

Michele DeGrazia, Banu Ahtam, Carolyn R Rogers-Vizena, Mark Proctor, Courtney Porter, Rutvi Vyas, Cynthia T Laurentys, Emily Bergling, Kara McLaughlin, Patricia Ellen Grant

Open access · bronzeAbstract read
In one paragraph

Article in Child neurology open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Michele DeGraziaCardiovascular and Critical Care, Boston Children's Hospital, Boston, MA, USA.ORCID https://orcid.org/0000-0002-7362-3394
Banu AhtamDepartment of Pediatrics, Harvard Medical School, Boston, MA, USA.
Carolyn R Rogers-VizenaDepartment of Plastic and Oral Surgery, Boston Children's Hospital, Boston, MA, USA.
Mark ProctorDepartment of Neurosurgery, Boston Children's Hospital, Boston, MA, USA.
Courtney PorterCardiovascular and Critical Care, Boston Children's Hospital, Boston, MA, USA.
Rutvi VyasDepartment of Pediatrics, Harvard Medical School, Boston, MA, USA.
Cynthia T LaurentysDepartment of Pediatrics, Harvard Medical School, Boston, MA, USA.
Emily BerglingCardiovascular and Critical Care, Boston Children's Hospital, Boston, MA, USA.
Kara McLaughlinHarvard School of Dental Medicine, Boston, MA, USA.
Patricia Ellen GrantDepartment of Pediatrics, Harvard Medical School, Boston, MA, USA.
Boston Children's Hospital · USHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis case report aims to assess a potential association between cranial asymmetry, brain deformation, and associated developmental delay. STUDY

designTwo infants born at ≥37 weeks pursuing cranial orthotic treatment for severe Deformational Plagiocephaly (DP) (cranial vault asymmetry index >8.75%) underwent developmental assessment using Mullen Scales of Early Learning (MSEL) and non-sedated brain structural and diffusion magnetic resonance imaging (MRI) prior to and following cranial orthotic treatment.

resultsIn both infants with DP, tractography results revealed alterations in the white matter pathways of the brain. Both infants also had low to low/normal visual receptivity and fine motor skills. After cranial orthotic treatment, cranial asymmetry improved but did not completely resolve, tractography demonstrated a change toward normalized white matter pathways, and visual receptivity and fine motor skills improved.

conclusionsThese preliminary findings suggest a potential link between DP, altered brain structures, and developmental assessment. Further investigation with a larger sample is warranted.

Indexed as

braindevelopmental delaydiffusion tensor imaginginfantMRIneurodevelopment

Identifiers

PMID32884966
PMCPMC7440724
OpenAlexW3079917782

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.