Evidence map›Paper›PMID 32884745›Full record

ArticleJournal of animal science and biotechnology2020

Tannic acid prevents post-weaning diarrhea by improving intestinal barrier integrity and function in weaned piglets.

Jie Yu, Yanyan Song, Bing Yu, Jun He, Ping Zheng, Xiangbing Mao, Zhiqing Huang, Yuheng Luo, Junqiu Luo, Hui Yan and 3 more

Abstract read
In one paragraph

Article in Journal of animal science and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Tannic acid as a multi-target regulator of intestinal barrier function in livestock.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Microorganisms · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Metabolomics and Antioxidant Activity of Valonea fromInternational journal of molecular sciences · 2025
    Article
  18. Article
  19. Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jie Yu *Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130 People's Republic of China.
Yanyan Song *Animal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130 People's Republic of China.
Bing YuAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130 People's Republic of China.
Jun HeAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130 People's Republic of China.
Ping ZhengAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130 People's Republic of China.
Xiangbing MaoAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130 People's Republic of China.
Zhiqing HuangAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130 People's Republic of China.
Yuheng LuoAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130 People's Republic of China.
Junqiu LuoAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130 People's Republic of China.
Hui YanAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130 People's Republic of China.
Quyuan WangAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130 People's Republic of China.
Huifen WangAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130 People's Republic of China.
Daiwen ChenAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu, 611130 People's Republic of China.ORCID 0000-0002-8351-7421

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTannic acid (TA) is potential to reduce diarrhea in weaning pigs, but knowledge about the influence of TA on intestinal barrier integrity and function is still scarce. This experiment was conducted to investigate the effects of dietary TA supplementation on growth performance, diarrhea rate, intestinal barrier integrity and function of weaned pigs.

methodsA total of 108 crossbred (Duroc × Landrace × Yorkshire) piglets, with an initial average body weight of 6.60 ± 0.27 kg, were allotted to 3 groups (6 pigs/pen and 6 replicates/group) in a randomized complete block design according to their gender and body weight. Piglets were fed the basal diet with 0 (control, CON), 0.2% and 1.0% TA, respectively. The trial lasted for 28 d.

resultsCompared with the CON group, dietary 0.2% and 1.0% TA supplementation didn't affect ADFI, ADG and F:G (

conclusionIn conclusion, dietary supplementation of 0.2% or 1.0% TA could effectively alleviate post-weaning diarrhea without altering growth performance in weaned piglets, which might be achieved by improving intestinal barrier integrity and function.

Indexed as

Intestine barrierPost-weaning diarrheaTannic acidWeaned piglets

Identifiers

PMID32884745
PMCPMC7460753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.