Evidence map›Paper›PMID 32884522›Full record

ArticleCase reports in oncology

Elevation of Memory Cytotoxic T Lymphocytes, Including Human T Lymphotropic Virus Type 1 Tax-Specific and Hepatitis Virus Type C-Specific Cytotoxic T Lymphocytes, in a Patient with Adult T-Cell Leukemia/Lymphoma and Hepatocellular Carcinoma.

Tatsuro Jo, Yohei Kaneko, Takayuki Oishi, Kaori Matsuzaka, Haruna Shioya, Takahiro Sakai, Hiroo Tomoinaga, Shizuka Hayashi, Masatoshi Matsuo, Jun Taguchi

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Tatsuro JoDepartment of Hematology, Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan.
Yohei KanekoDepartment of Laboratory, Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan.
Takayuki OishiDepartment of Gastroenterology, Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan.
Kaori MatsuzakaDepartment of Laboratory, Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan.
Haruna ShioyaDepartment of Laboratory, Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan.
Takahiro SakaiDepartment of Laboratory, Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan.
Hiroo TomoinagaDepartment of Laboratory, Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan.
Shizuka HayashiDepartment of Laboratory, Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan.
Masatoshi MatsuoDepartment of Hematology, Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan.
Jun TaguchiDepartment of Hematology, Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan.
Japanese Red Cross Society, Japan · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we present the case of a patient who suffered from adult T-cell leukemia/lymphoma (ATLL) and hepatocellular carcinoma (HCC) after obtaining a sustained virological response following treatment with a direct-acting antiviral (DAA) at different points in time. The patient went into complete remission (CR) for ATLL. Unfortunately, subsequent relapse of ATLL was observed. This situation was overcome using chemotherapy with pegylated interferon alpha-2b. Human T lymphotropic virus type 1 Tax-specific cytotoxic T lymphocytes (CTLs) were recognized after obtaining second CR, and those CTLs have been maintained for many years. After 4 years from the second CR, chronic hepatitis type C was treated with a DAA, and sustained virological response was attained. However, the occurrence of HCC was detected. Surprisingly, the tumor disappeared spontaneously. Hepatitis virus type C-specific CTLs were also detected in the patient. T-cell receptor (TCR)

Indexed as

Adult T-cell leukemia/lymphomaCytotoxic T lymphocyteHepatitis virus type CHepatocellular carcinomaHuman T lymphotropic virus type 1 Tax

Identifiers

PMID32884522
PMCPMC7443665
OpenAlexW3041624452

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.