Evidence map›Paper›PMID 32884258›Full record

ArticleInternational journal of nanomedicine2020

The Effects Study of Isoniazid Conjugated Multi-Wall Carbon Nanotubes Nanofluid on

Shahab Zomorodbakhsh, Yasamin Abbasian, Maryam Naghinejad, Mojgan Sheikhpour

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Antimicrobial efficacy of carbon nanotube-based nano drug onBiochemistry and biophysics reports · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Shahab ZomorodbakhshDepartment of Chemistry, Mahshahr Branch, Islamic Azad University, Mahshahr, Iran.
Yasamin AbbasianFaculty of Pharmacy and Pharmaceutical Sciences, Islamic Azad University, Tehran, Iran.
Maryam NaghinejadDepartment of Mycobacteriology and Pulmonary Research, Pasteur Institute of Iran, Tehran, Iran.ORCID 0000-0001-9926-7474
Mojgan SheikhpourDepartment of Mycobacteriology and Pulmonary Research, Pasteur Institute of Iran, Tehran, Iran.ORCID 0000-0001-8802-7520
Pasteur Institute of Iran · IRIslamic Azad University Mahshahr · IRIslamic Azad University Pharmaceutical Sciences Branch · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTuberculosis (TB) has always been recognized as one of the fatal infectious diseases, which is caused by

methodsINH-conjugated functionalized MWCNTs were prepared, using a reflux system. The characterization of the obtained nano-drug was performed by the elemental analyses of total nitrogen, hydrogen, carbon and sulfur (CHNS), Raman spectroscopy, Fourier transform infrared (FTIR), transmission electron microscopy (TEM), and scanning electron microscopy (SEM) methods. The nanofluid of nano-drug was prepared by the ultrasonic method, and the related antibacterial effect studies were carried out on the two strains of M.tb.

resultsThe antimicrobial effect of INH-conjugated MWCNTs was found to be much better at low concentrations than the pure drug in all of the strains.

conclusionSince one of the main antimicrobial mechanisms of MWCNTs is through the destruction of the bacterial cell wall, in addition to its antimicrobial effects, it increased the drug delivery of INH at lower doses compared to drug alone. So, the nanofluid, containing INH-conjugated MWCNTs, had a better lethal effect on a variety of M.tb strains than that of the drug alone.

Indexed as

Antitubercular AgentsDrug Delivery SystemsHumansIsoniazidMicrobial Sensitivity TestsMicroscopy, Electron, ScanningMicroscopy, Electron, TransmissionMycobacterium tuberculosisNanostructuresNanotubes, CarbonSpectroscopy, Fourier Transform InfraredSpectrum Analysis, RamanTuberculosisAntitubercular AgentsIsoniazidNanotubes, Carbonisoniazidmulti-wall carbon nanotubesMycobacterium tuberculosisnano-drugnanofluid

Identifiers

PMID32884258
PMCPMC7434524
OpenAlexW3048391154

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.