Observational studyJournal of the American Society of Nephrology : JASN2021
AKI in Hospitalized Patients with COVID-19.
Observational study in Journal of the American Society of Nephrology : JASN, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 432 papers, 3 of them syntheses that pooled it.
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Who cites it
432 citing papers in PubMed, 3 syntheses or guidelines pooled it, 698 citations in OpenAlex.
- Global geographic and socioeconomic disparities in COVID-associated acute kidney injury: a systematic review and meta-analysis.Journal of global health · 2025Pooled it
- Long-term renal outcomes of patients with COVID-19: a meta-analysis of observational studies.Journal of nephrology · 2023Pooled it
- Acute kidney injury in COVID-19 patients receiving remdesivir: A systematic review and meta-analysis of randomized clinical trials.Clinics (Sao Paulo, Brazil) · 2023Pooled it
- Four-organ SOFA score as a potential tool to triage use of continuous kidney replacement therapy in COVID-19 patients with acute kidney injury: a retrospective two-center study.Renal failure · 2026Article
- Acute and chronic kidney injury following COVID-19 infection and vaccination: a narrative review.European journal of translational myology · 2026Article
- Renal function dynamics in COVID-19: exploring biomarker interactions with D-dimer and C-reactive proteins.Bioscience reports · 2026Article
- Acute Kidney Injury in Internal Medicine Wards During a Period of Wartime Healthcare System Disruption: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Seasonal Variations in the Risk of Outpatient Acute Kidney Injury in Patients with Chronic Kidney Disease.Diagnostics (Basel, Switzerland) · 2026Article
- The global epidemiology of acute kidney injury: challenges and opportunities.Nature reviews. Nephrology · 2026Review
- The risk of kidney disease increases following SARS-CoV-2 infection compared to influenza.Communications medicine · 2026Article
- Acute kidney injury among hospitalized COVID-19 patients in Sudan: a single-centre retrospective study.Conflict and health · 2026Article
- Article
- Prerenal acute kidney injury diagnosed by urinary indices in a COVID-19 patient: A critical care case report.IDCases · 2026Article
- Development and Validation of a Nomogram for Predicting Acute Kidney Injury in Acute Respiratory Distress Syndrome.Journal of inflammation research · 2026Article
- Right Atrium Large Masses Due to Endocarditis Following Permcath Insertion After Covid-19-Induced Renal Failure.Iranian journal of pathology · 2026Article
- Clinical characteristics and mortality outcomes of acute kidney injury following COVID-19 infection in patients with chronic kidney disease at different stages.BMC infectious diseases · 2025Article
- Baseline medication profile and risk of CYP3A4 mediated drug-drug interactions among COVID-19 hospitalized patients in Spain.BMC infectious diseases · 2025Observational
- Long COVID and the kidney.Nature reviews. Nephrology · 2025Review
- The blood urea nitrogen-to-creatinine ratio is associated with acute kidney injury among COVID-19 patients.Renal failure · 2025Article
- Impact of COVID-19 on Renal Function: Analysis of Acute Kidney Injury Across Three Pandemic Waves.Biomedicines · 2025Article
372 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
33 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundEarly reports indicate that AKI is common among patients with coronavirus disease 2019 (COVID-19) and associated with worse outcomes. However, AKI among hospitalized patients with COVID-19 in the United States is not well described.
methodsThis retrospective, observational study involved a review of data from electronic health records of patients aged ≥18 years with laboratory-confirmed COVID-19 admitted to the Mount Sinai Health System from February 27 to May 30, 2020. We describe the frequency of AKI and dialysis requirement, AKI recovery, and adjusted odds ratios (aORs) with mortality.
resultsOf 3993 hospitalized patients with COVID-19, AKI occurred in 1835 (46%) patients; 347 (19%) of the patients with AKI required dialysis. The proportions with stages 1, 2, or 3 AKI were 39%, 19%, and 42%, respectively. A total of 976 (24%) patients were admitted to intensive care, and 745 (76%) experienced AKI. Of the 435 patients with AKI and urine studies, 84% had proteinuria, 81% had hematuria, and 60% had leukocyturia. Independent predictors of severe AKI were CKD, men, and higher serum potassium at admission. In-hospital mortality was 50% among patients with AKI versus 8% among those without AKI (aOR, 9.2; 95% confidence interval, 7.5 to 11.3). Of survivors with AKI who were discharged, 35% had not recovered to baseline kidney function by the time of discharge. An additional 28 of 77 (36%) patients who had not recovered kidney function at discharge did so on posthospital follow-up.
conclusionsAKI is common among patients hospitalized with COVID-19 and is associated with high mortality. Of all patients with AKI, only 30% survived with recovery of kidney function by the time of discharge.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.