Evidence map›Paper›PMID 32883697›Full record

ReviewMolecular cancer research : MCR2021

CYLD Alterations in the Tumorigenesis and Progression of Human Papillomavirus-Associated Head and Neck Cancers.

Zhibin Cui, Hyunseok Kang, Jennifer R Grandis, Daniel E Johnson

Open access · bronzeAbstract readReview
In one paragraph

Review in Molecular cancer research : MCR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Genomic Enrichment and Functional Impact of TP53 and CYLD Alterations in Recurrent and Metastatic HPV-Associated Head and Neck Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. AKT and DUBs: a bidirectional relationship.Cellular & molecular biology letters · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. The therapeutic potential of RNA m(6)A in lung cancer.Cell communication and signaling : CCS · 2024
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Repressive Control of Keratinocyte Cytoplasmic Inflammatory Signaling.International journal of molecular sciences · 2023
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zhibin CuiDepartment of Otolaryngology - Head and Neck Surgery, University of California San Francisco, San Francisco, California. Zhibin.cui@ucsf.edu.
Hyunseok KangDepartment of Medicine, University of California San Francisco, San Francisco, California.ORCID https://orcid.org/0000-0001-5758-8202
Jennifer R GrandisDepartment of Otolaryngology - Head and Neck Surgery, University of California San Francisco, San Francisco, California.
Daniel E JohnsonDepartment of Otolaryngology - Head and Neck Surgery, University of California San Francisco, San Francisco, California.
University of California, San Francisco · US

Funding

Integrating genomics and the protein interactome for HPV+ head and neck cancer therapyR35CA231998 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN · 2018 to 2024
$6.2M
PI3K Pathway Mutations in Head and Neck CancerR01DE023685 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GRANDIS, JENNIFER RUBIN, JOHNSON, DANIEL E · 2014 to 2023
$5.1M
Targeting STAT3 to enhance anti-tumor immunityR01DE028289 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN, JOHNSON, DANIEL E · 2019 to 2023
$3.2M
NCI NIH HHS R35 CA231998NIDCR NIH HHS R01 DE023685NIDCR NIH HHS R01 DE028289
6 · The paper itself

Abstract

Genetic alterations of

Indexed as

CarcinogenesisDeubiquitinating Enzyme CYLDDisease ProgressionHead and Neck NeoplasmsHumansNeoplasm MetastasisPapillomaviridaeCYLD protein, humanDeubiquitinating Enzyme CYLD

Identifiers

PMID32883697
PMCPMC7840145
OpenAlexW3082196460

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.