Evidence map›Paper›PMID 32883670›Full record

ReviewAJNR. American journal of neuroradiology2020

MRI Brain Findings in 126 Patients with COVID-19: Initial Observations from a Descriptive Literature Review.

E Gulko, M L Oleksk, W Gomes, S Ali, H Mehta, P Overby, F Al-Mufti, A Rozenshtein

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04745611 (Neurological and Neuropsychological Sequelae of COVID-19 Infection), which is not on this map. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04745611 completednot on this map

Neurological and Neuropsychological Sequelae of COVID-19 Infection

Typeobservational_patient_registrySponsorMaastricht UniversityRan2020 to 2022Enrolled329ConditionsCOVID-19 InfectionArmsMRI, Neuropsychological assessment, Questionnaires Patient, Questionnaires Family
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 86 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
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  5. Review
  6. Article
  7. Article
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  11. Review
  12. Article
  13. Acute Neurological Complications of Coronavirus Disease.Neuroimaging clinics of North America · 2023
    Review
  14. Coronavirus Disease: Subacute to Chronic Neuroimaging Findings.Neuroimaging clinics of North America · 2023
    Review
  15. Is a high chest CT severity score a risk factor for an increased incidence of long-term neuroimaging findings after COVID-19?Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2023
    Article
  16. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

E GulkoFrom the Department of Radiology (E.G., W.G., S.A., H.M.), Division of Neuroradiology Edwin.Gulko@wmchealth.org.ORCID 0000-0002-3163-6576
M L OlekskNew York Medical College (M.L.O.), Valhalla, New York.ORCID 0000-0002-0007-6035
W GomesFrom the Department of Radiology (E.G., W.G., S.A., H.M.), Division of Neuroradiology.ORCID 0000-0002-5046-1505
S AliFrom the Department of Radiology (E.G., W.G., S.A., H.M.), Division of Neuroradiology.ORCID 0000-0003-4957-9087
H MehtaFrom the Department of Radiology (E.G., W.G., S.A., H.M.), Division of Neuroradiology.ORCID 0000-0002-5018-216X
P OverbyDepartment of Pediatrics (P.O.).ORCID 0000-0002-8303-995X
F Al-MuftiDepartment of Neurology (F.A.M.), Westchester Medical Center, Valhalla, New York.ORCID 0000-0003-4461-7005
A RozenshteinDepartment of Radiology (A.R.), Division of Cardiothoracic Imaging, Westchester Medical Center, Valhalla, New York.ORCID 0000-0001-9092-0422
MACOM (United States) · USWestchester Medical Center · USeHealth Initiative · USNew York Medical College · USUniversity of Oulu · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeRecently, numerous investigational studies, case series, and case reports have been published describing various MR imaging brain findings in patients with COVID-19. The purpose of this literature review was to compile and analyze brain MR imaging findings in patients with COVID-19-related illness. MATERIALS AND

methodsLiterature searches of PubMed, publicly available Internet search engines, and medical journal Web sites were performed to identify articles published before May 30, 2020 that described MR imaging brain findings in patients with COVID-19.

resultsTwenty-two articles were included in the analysis: 5 investigational studies, 6 case series, and 11 case reports, encompassing MR imaging of the brain in 126 patients. The articles originated from 7 different countries and were published in 14 medical journals. MR imaging brain findings included specific diagnoses (such as acute infarct, posterior reversible encephalopathy syndrome) or specific imaging features (such as cortical FLAIR signal abnormality, microhemorrhages).

conclusionsThe most frequent diagnoses made on brain MR imaging in patients with COVID-19 were acute and subacute infarcts. Other common findings included a constellation of leukoencephalopathy and microhemorrhages, leptomeningeal contrast enhancement, and cortical FLAIR signal abnormality.

Indexed as

BrainBrain DiseasesCOVID-19FemaleHumansMagnetic Resonance ImagingMaleSARS-CoV-2Young Adult

Identifiers

PMID32883670
PMCPMC7963260
OpenAlexW3081888891

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.