Evidence map›Paper›PMID 32883417›Full record

ReviewJournal of the American College of Cardiology2020

Coronary Computed Tomography Angiography From Clinical Uses to Emerging Technologies: JACC State-of-the-Art Review.

Khaled M Abdelrahman, Marcus Y Chen, Amit K Dey, Renu Virmani, Aloke V Finn, Ramzi Y Khamis, Andrew D Choi, James K Min, Michelle C Williams, Andrew J Buckler and 10 more

Open access · greenAbstract readReview
In one paragraph

Review in Journal of the American College of Cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 147 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
147citing papers in PubMed, 1 pooled it
14.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

147 citing papers in PubMed, 1 synthesis or guideline pooled it, 276 citations in OpenAlex.

  1. Pooled it
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  12. Coronary artery anomalies: contemporary approaches to risk stratification and management.European heart journal supplements : journal of the European Society of Cardiology · 2026
    Article
  13. First scan, then treat: 10 years of the SCOT-HEART study.European heart journal supplements : journal of the European Society of Cardiology · 2026
    Article
  14. Article
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87 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 14 institutions in 2 countries.

Khaled M AbdelrahmanNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland.
Marcus Y ChenNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland.
Amit K DeyNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland.
Renu VirmaniDepartment of Pathology, CVPath Institute, Gaithersburg, Maryland.
Aloke V FinnDepartment of Pathology, CVPath Institute, Gaithersburg, Maryland.
Ramzi Y KhamisVascular Sciences Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom.
Andrew D ChoiDivision of Cardiology and Department of Radiology, The George Washington University School of Medicine, Washington, DC.
James K MinDepartment of Radiology, New York-Presbyterian Hospital and Weill Cornell Medicine, New York, New York.
Michelle C WilliamsBritish Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom; Edinburgh Imaging, Queen's Medical Research Institute University of Edinburgh, Edinburgh, United Kingdom.
Andrew J BucklerElucid Bioimaging, Boston, Massachusetts.
Charles A TaylorHeartFlow Inc., Redwood City, California.
Campbell RogersHeartFlow Inc., Redwood City, California.
Habib SamadyDivision of Cardiology, Emory University School of Medicine, Atlanta, Georgia.
Charalambos AntoniadesDivision of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Leslee J ShawDepartment of Radiology, New York-Presbyterian Hospital and Weill Cornell Medicine, New York, New York.
Matthew J BudoffLundquist Institute at Harbor-UCLA Medical Center, Torrance, California.
Udo HoffmannDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Ron BlanksteinDepartments of Medicine (Cardiovascular Division) and Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Jagat NarulaZena and Michael A. Wiener Cardiovascular Institute, Marie-Josée and Henry R. Kravis Center for Cardiovascular Health Icahn School of Medicine at Mount Sinai, Mount Sinai Heart, New York, New York.
Nehal N MehtaNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland. Electronic address: nehal.mehta@nih.gov.
National Institutes of Health · USCVPath Institute · USHeartFlow (United States) · USNewYork–Presbyterian Hospital · USBrigham and Women's Hospital · USBritish Heart Foundation · GBCardiovascular Institute of the South · USElucid Bioimaging · USEmory University · USGeorge Washington University · USHarvard University · USImperial College London · GBUCLA Medical Center · USUniversity of Oxford · GB

Funding

Human Translational Studies of Inflammation and Cardiometabolic Diseases: The Psoriasis, Atherosclerosis and Cardiometabolic disease (PACI) InitiativeZIAHL006193 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI SACK, MICHAEL · 2014 to 2023
$25.0M
In-vitro and Pre-clinical Translational Studies of Inflammation and AtherosclerosisZIAHL006235 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI SACK, MICHAEL · 2018 to 2023
$6.7M
Cardiac MR and CT ResearchT32HL076136 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI NEILAN, TOMAS G · 2004 to 2019
$4.9M
IL1beta signaling in SMCpromotes beneficial changes in late stage atherosclerotic lesion pathogenesisR01HL141425 · NHLBI · UNIVERSITY OF VIRGINIA · PI OWENS, GARY K · 2019 to 2022
$3.1M
PROMISE Trial: Substudy to Assess for Effective Dose of RadiationR01HL109711 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI EINSTEIN, ANDREW · 2011 to 2015
$2.5M
Cardiovascular Imaging in Ischemic Heart DiseaseK24HL113128 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI HOFFMANN, UDO · 2012 to 2020
$1.1M
British Heart Foundation FS/16/15/32047British Heart Foundation FS/17/16/32560NHLBI NIH HHS K24 HL113128NHLBI NIH HHS R01 HL109711NHLBI NIH HHS R01 HL141425NHLBI NIH HHS T32 HL076136
6 · The paper itself

Abstract

Evaluation of coronary artery disease (CAD) using coronary computed tomography angiography (CCTA) has seen a paradigm shift in the last decade. Evidence increasingly supports the clinical utility of CCTA across various stages of CAD, from the detection of early subclinical disease to the assessment of acute chest pain. Additionally, CCTA can be used to noninvasively quantify plaque burden and identify high-risk plaque, aiding in diagnosis, prognosis, and treatment. This is especially important in the evaluation of CAD in immune-driven conditions with increased cardiovascular disease prevalence. Emerging applications of CCTA based on hemodynamic indices and plaque characterization may provide personalized risk assessment, affect disease detection, and further guide therapy. This review provides an update on the evidence, clinical applications, and emerging technologies surrounding CCTA as highlighted at the 2019 National Heart, Lung and Blood Institute CCTA Summit.

Indexed as

Biomedical TechnologyChest PainComputed Tomography AngiographyCoronary AngiographyCoronary Artery DiseaseHumansReview Literature as TopicRisk AssessmentVascular Calcificationatherosclerosiscoronary artery diseasecoronary computed tomography angiography

Identifiers

PMID32883417
PMCPMC7480405
OpenAlexW3082327238

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.