Evidence map›Paper›PMID 32883344›Full record

ArticleVeterinary research2020

Canine Parvovirus is diagnosed and neutralized by chicken IgY-scFv generated against the virus capsid protein.

Shikun Ge, Long Xu, Ben Li, Fagang Zhong, Xiang Liu, Xiaoying Zhang

Open access · goldAbstract read
In one paragraph

Article in Veterinary research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Latest Findings in Immunoglobulin Y Technologies and Applications.International journal of molecular sciences · 2025
    Review
  4. Avian Antibodies as Potential Therapeutic Tools.Antibodies (Basel, Switzerland) · 2025
    Review
  5. Preparation and evaluation of homologous IgG on canine parvovirus.Iranian journal of veterinary research · 2025
    Article
  6. Preparation of Bispecific IgY-scFvs Inhibition Adherences of EnterotoxigenicInternational journal of molecular sciences · 2024
    Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Anti-Vaccines · 2021
    Article
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Shikun GeChinese-German Joint Laboratory for Natural Product Research, Key Laboratory of Biological Resources and Ecological Environment of Qinba Areas, School of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong, China.
Long XuChinese-German Joint Laboratory for Natural Product Research, Key Laboratory of Biological Resources and Ecological Environment of Qinba Areas, School of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong, China.
Ben LiChinese-German Joint Laboratory for Natural Product Research, Key Laboratory of Biological Resources and Ecological Environment of Qinba Areas, School of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong, China.
Fagang ZhongState Key Laboratory for Sheep Genetic Improvement and Healthy Production, Xinjiang Academy of Agricultural and Reclamation Science, Shihezi, China.
Xiang LiuChinese-German Joint Laboratory for Natural Product Research, Key Laboratory of Biological Resources and Ecological Environment of Qinba Areas, School of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong, China.
Xiaoying ZhangChinese-German Joint Laboratory for Natural Product Research, Key Laboratory of Biological Resources and Ecological Environment of Qinba Areas, School of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong, China. zhang@bio.uminho.pt.ORCID http://orcid.org/0000-0002-0055-7322
Shaanxi University of Technology · CNXinjiang Academy of Agricultural and Reclamation Science · CN

Funding

Incubation Project on State Key Laboratory of Biological Resources and Ecological Environment of Qinba Areas SLGPT2019KF04-04National Natural Science Foundation of China 31572556National Natural Science Foundation of China 31873006
6 · The paper itself

Abstract

Canine parvovirus (CPV) can cause acute and highly contagious bloody enteritis in dog. To obtain antibodies against CPV, hens were immunized with virus-like particles (VLP) of CPV-VP2. The IgY single chain fragment variables (scFv) were generated by T7 phage display system and expressed in E. coli system. The titer of the primary scFv library reached to 1.5 × 10

Indexed as

AnimalsAntibodies, NeutralizingAntibodies, ViralCapsid ProteinsChickensDog DiseasesDogsEnzyme-Linked Immunosorbent AssayFemaleImmunoglobulinsMolecular Docking SimulationParvoviridae InfectionsParvovirus, CanineSingle-Chain AntibodiesAntibodies, NeutralizingAntibodies, ViralCapsid ProteinsIgYImmunoglobulinsSingle-Chain AntibodiesIgY-Technologyinfectious animal diseasesparvovirusphage display systemvirus diseases

Identifiers

PMID32883344
PMCPMC7468180
OpenAlexW3082461960

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.