Evidence map›Paper›PMID 32883251›Full record

ArticleBMC public health2020

Tuberculosis-related stigma among adults presenting for HIV testing in KwaZulu-Natal, South Africa.

Kristina L Bajema, Rachel W Kubiak, Brandon L Guthrie, Susan M Graham, Sabina Govere, Hilary Thulare, Mahomed-Yunus Moosa, Connie Celum, Paul K Drain

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.3field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

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  8. Perceived stigma among people with TB and household contacts.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Kristina L BajemaDepartment of Medicine, University of Washington, Seattle, USA. kbajema@uw.edu.ORCID http://orcid.org/0000-0002-3229-5590
Rachel W KubiakDepartment of Epidemiology, University of Washington, Seattle, USA.
Brandon L GuthrieDepartment of Epidemiology, University of Washington, Seattle, USA.
Susan M GrahamDepartment of Medicine, University of Washington, Seattle, USA.
Sabina GovereAIDS Healthcare Foundation, Durban, South Africa.
Hilary ThulareAIDS Healthcare Foundation, Durban, South Africa.
Mahomed-Yunus MoosaDepartment of Infectious Diseases, University of KwaZulu-Natal, Durban, South Africa.
Connie CelumDepartment of Medicine, University of Washington, Seattle, USA.
Paul K DrainDepartment of Medicine, University of Washington, Seattle, USA.
University of Washington · USAIDS Healthcare Foundation · ZAUniversity of KwaZulu-Natal · ZA

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Judith Tsui · 1988 to 2026
$104.9M
The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ROBERT A. PARKER · 2004 to 2026
$94.4M
Clinic-based Screening to Prevent HIV-associated Cryptococcal MortalityK23AI108293 · NIAID · UNIVERSITY OF WASHINGTON · PI DRAIN, PAUL K · 2014 to 2018
$928k
NIAID NIH HHS K23 AI108293NIAID NIH HHS P30 AI027757NIAID NIH HHS P30 AI060354
6 · The paper itself

Abstract

backgroundTuberculosis (TB)-related stigma presents a major barrier to care of persons with TB through its impact on treatment initiation and retention in care. This is particularly challenging in settings with high prevalence of both TB and HIV where fear of HIV/AIDS can amplify stigma surrounding TB. The purpose of this study was to validate a TB stigma scale for use among persons presenting for outpatient HIV screening in the Umlazi township of South Africa and evaluate factors associated with TB-related stigma in this high HIV burden setting.

methodsIn this cross-sectional study, we measured TB-related stigma in adults prior to HIV testing using a 12-item scale designed to assess experienced and felt TB-related stigma.

resultsAmong 848 adults, mean age was 32 years, 54% were male, and the median TB stigma score was 19 of 36 (interquartile range 15-23). We identified two factors in the stigma scale which had excellent reliability (Cronbach's alpha 0.85, 0.89). Persons with high TB stigma were more likely to be male (adjusted relative risk ratio [aRRR] 1.56, 95% confidence interval [CI] 1.11-2.28) and have accurate knowledge of TB transmission (aRRR 1.90, 95% CI 1.16-3.10) as compared to those with low stigma. Variables not significantly associated with stigma in the multivariate model included education, income, prior TB or HIV diagnoses, and depression.

conclusionsMale sex and TB knowledge were associated with higher TB stigma in an outpatient HIV clinic in a South African township. Identifying risk factors associated with stigma will be important to guide stigma reduction interventions.

Indexed as

HIV InfectionsTuberculosisAdultCross-Sectional StudiesFemaleHIV TestingHumansMaleReproducibility of ResultsSouth AfricaHIVSouth AfricaStigmaTuberculosis

Identifiers

PMID32883251
PMCPMC7469347
OpenAlexW3081719767

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.