Evidence map›Paper›PMID 32883103›Full record

ArticleCirculation. Cardiovascular interventions2020

Association Between 90-Minute Door-to-Balloon Time, Selective Exclusion of Myocardial Infarction Cases, and Access Site Choice: Insights From the Cardiac Care Outcomes Assessment Program (COAP) in Washington State.

Ashwin S Nathan, Swathi Raman, Nancy Yang, Ian Painter, Sameed Ahmed M Khatana, Elias J Dayoub, Howard C Herrmann, Robert W Yeh, Peter W Groeneveld, Jacob A Doll and 4 more

Abstract readComparative Study
In one paragraph

Article in Circulation. Cardiovascular interventions, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Point-of-Care Ultrasound Use in Cardiac Arrest Patients.Diagnostics (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Ashwin S NathanCardiovascular Division, Hospital of the University of Pennsylvania, Philadelphia (A.S.N., S.A.M.K., H.C.H., J.G., A.C.F.).
Swathi RamanCollege of Arts and Sciences (S.R., N.Y.), University of Pennsylvania, Philadelphia, PA.
Nancy YangCollege of Arts and Sciences (S.R., N.Y.), University of Pennsylvania, Philadelphia, PA.
Ian PainterDivision of Cardiology, University of Washington, Seattle (I.P., J.A.D., J.M.M., R.S.H.).
Sameed Ahmed M KhatanaCardiovascular Division, Hospital of the University of Pennsylvania, Philadelphia (A.S.N., S.A.M.K., H.C.H., J.G., A.C.F.).
Elias J DayoubLeonard Davis Institute of Health Economics (A.S.N., S.A.M.K., E.J.D., P.W.G., J.G., A.C.F.), University of Pennsylvania, Philadelphia, PA.
Howard C HerrmannCardiovascular Division, Hospital of the University of Pennsylvania, Philadelphia (A.S.N., S.A.M.K., H.C.H., J.G., A.C.F.).
Robert W YehRichard and Susan Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Boston, MA (R.W.Y.).
Peter W GroeneveldLeonard Davis Institute of Health Economics (A.S.N., S.A.M.K., E.J.D., P.W.G., J.G., A.C.F.), University of Pennsylvania, Philadelphia, PA.
Jacob A DollDivision of Cardiology, University of Washington, Seattle (I.P., J.A.D., J.M.M., R.S.H.).
James M McCabeDivision of Cardiology, University of Washington, Seattle (I.P., J.A.D., J.M.M., R.S.H.).
Ravi S HiraDivision of Cardiology, University of Washington, Seattle (I.P., J.A.D., J.M.M., R.S.H.).
Jay GiriCardiovascular Division, Hospital of the University of Pennsylvania, Philadelphia (A.S.N., S.A.M.K., H.C.H., J.G., A.C.F.).
Alexander C FanaroffCardiovascular Division, Hospital of the University of Pennsylvania, Philadelphia (A.S.N., S.A.M.K., H.C.H., J.G., A.C.F.).

Funding

Association of Health Insurance with Access to Cardiovascular CareK23HL153772 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI KHATANA, SAMEED AHMED MUSTAFA · 2020 to 2024
$981k
NHLBI NIH HHS K23 HL153772
6 · The paper itself

Abstract

backgroundFor patients presenting with ST-segment-elevation myocardial infarction, national quality initiatives monitor hospitals' proportion of cases with door-to-balloon (D2B) time under 90 minutes. Hospitals are allowed to exclude patients from reporting and may modify behavior to improve performance. We sought to identify whether there is a discontinuity in the number of cases included in the D2B time metric at 90 minutes and whether operators were increasingly likely to pursue femoral access in patients with less time to meet the 90-minute quality metric.

methodsAdult patients with ST-segment-elevation myocardial infarction undergoing primary percutaneous coronary intervention from 2011 to 2018 were identified from the Cardiac Care Outcomes Assessment Program, a quality improvement registry in Washington state. We used the regression discontinuity framework to test for discontinuity at 90 minutes among the included cases. We defined a novel variable, remaining D2B as 90 minutes minus the time between hospital arrival and catheterization laboratory arrival. We estimated multivariable logistic regression models to assess the relationship between remaining D2B time and access site.

resultsA total of 19 348 patients underwent primary percutaneous coronary intervention and were included in the analysis. Overall, 7436 (38.4%) were excluded from the metric. There appeared to be a visual discontinuity in included cases around 90 minutes; however, local quadratic regression around the 90-minute cutoff did not reveal evidence of a significant discontinuity (

conclusionsAmong patients undergoing percutaneous coronary intervention for ST-segment-elevation myocardial infarction, we did not find evidence of a statistically significant discontinuity in the frequency of included cases around 90 minutes or an increased preference for femoral access correlated with decreasing time to meet the 90-minute D2B time quality metric. Together, these findings indicate no evidence of widespread inappropriate methods to improve performance on D2B time metrics.

Indexed as

Catheterization, PeripheralFemoral ArteryOutcome and Process Assessment, Health CarePercutaneous Coronary InterventionRadial ArteryTime-to-TreatmentAgedFemaleHumansMaleMiddle AgedPractice Patterns, Physicians'PuncturesQuality Indicators, Health CareRegistriesRisk Assessmentassociationcatheterizationhospitalsmyocardial infarctionpercutaneous coronary intervention

Identifiers

PMID32883103
PMCPMC9125502

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.