ReviewBioTechniques2020
Contrast-enhanced ultrasound for the assessment of placental development and function.
Review in BioTechniques, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 30 citations in OpenAlex.
- Phosphorescence lifetime microscopy and contrast-enhanced ultrasound imaging revealed strong left-to-right intraventricular shunt in anesthetized Xenopus laevis.The journal of physiological sciences : JPS · 2026Article
- Spatiotemporal characterization of placental hypoxia and microvascular dysfunction in a preeclampsia rat model using photoacoustic and contrast-enhanced ultrasound.Quantitative imaging in medicine and surgery · 2026Article
- Comparison of Laser Doppler Flowmetry With Contrast-Enhanced Ultrasound to Approximate Placental Microvascular Blood Flow in the African Green Monkey (Chlorocebus aethiops sabaeus).Journal of medical primatology · 2026Article
- Modelling maternal cardiovascular adaptation to pregnancy: a scoping review.BMC pregnancy and childbirth · 2025Article
- Controversies in contrast-enhanced ultrasound (CEUS): pregnancy, paediatric, abdominal trauma, complex renal cysts, and endovascular aortic repair follow-up.Insights into imaging · 2025Article
- Article
- Safety of contrast-enhanced ultrasound using microbubbles in human pregnancy: A scoping review.Ultraschall in der Medizin (Stuttgart, Germany : 1980) · 2025Article
- Nanomedicines for Improved Management of Ectopic Pregnancy: A Narrative Review.Small (Weinheim an der Bergstrasse, Germany) · 2024Review
- B-Flow/Spatiotemporal Image Correlation M-Mode and Contrast-Enhanced/Microbubble Ultrasonography Quantification of Spiral Artery Distensibility and Placental Intervillous Perfusion in the First Trimester in a Primate Model of Impaired Spiral Artery Remodeling.Ultrasound in medicine & biology · 2023Article
- Maternal-fetal cross-talk via the placenta: influence on offspring development and metabolism.Development (Cambridge, England) · 2023Review
- The human placenta project: Funded studies, imaging technologies, and future directions.Placenta · 2023Review
- Placental assessment using spectral analysis of the envelope of umbilical venous waveforms in sheep.Placenta · 2023Article
- Biogenic Imaging Contrast Agents.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Review
- Contrast-Enhanced Ultrasonography (CEUS) in Imaging of the Reproductive System in Dogs: A Literature Review.Animals : an open access journal from MDPI · 2023Review
- Utilizing Contrast-Enhanced Ultrasonography with Phosphatidylserine Microbubbles to Detect Placental Inflammation in Rhesus Macaques.Molecules (Basel, Switzerland) · 2023Article
- Three-Dimensional Deep-Tissue Functional and Molecular Imaging by Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT).IEEE transactions on medical imaging · 2022Article
- Nanotechnologies in Obstetrics and Cancer during Pregnancy: A Narrative Review.Journal of personalized medicine · 2022Review
- Making decisions about radiological imaging in pregnancy.BMJ (Clinical research ed.) · 2022Article
- A 10-Year Retrospective Review of Prenatal Applications, Current Challenges and Future Prospects of Three-Dimensional Sonoangiography.Diagnostics (Basel, Switzerland) · 2021Review
- Novel Technologies for Target Delivery of Therapeutics to the Placenta during Pregnancy: A Review.Genes · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The use of contrast agents as signal enhancers during ultrasound improves visualization and the diagnostic utility of this technology in medical imaging. Although widely used in many disciplines, contrast ultrasound is not routinely implemented in obstetrics, largely due to safety concerns of administered agents for pregnant women and the limited number of studies that address this issue. Here the microbubble characteristics that make them beneficial for enhancement of the blood pool and the quantification of real-time imaging are reviewed. Literature from pregnant animal model studies and safety assessments are detailed, and the potential for contrast-enhanced ultrasound to provide clinically relevant data and benefit our understanding of early placental development and detection of placental dysfunction is discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.