Evidence map›Paper›PMID 32883045›Full record

ArticleToxins2020

Clostridial C3 Toxins Enter and Intoxicate Human Dendritic Cells.

Maximilian Fellermann, Christina Huchler, Lea Fechter, Tobias Kolb, Fanny Wondany, Daniel Mayer, Jens Michaelis, Steffen Stenger, Kevin Mellert, Peter Möller and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxins, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Toxins · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Maximilian FellermannInstitute of Pharmacology and Toxicology, University of Ulm Medical Center, 89081 Ulm, Germany.
Christina HuchlerInstitute of Pharmacology and Toxicology, University of Ulm Medical Center, 89081 Ulm, Germany.
Lea FechterInstitute of Pharmacology and Toxicology, University of Ulm Medical Center, 89081 Ulm, Germany.
Tobias KolbInstitute of Pharmacology and Toxicology, University of Ulm Medical Center, 89081 Ulm, Germany.
Fanny WondanyInstitute of Biophysics, Ulm University, 89081 Ulm, Germany.
Daniel MayerInstitute for Medical Microbiology and Hygiene, University of Ulm Medical Center, 89081 Ulm, Germany.
Jens MichaelisInstitute of Biophysics, Ulm University, 89081 Ulm, Germany.ORCID 0000-0002-2739-4172
Steffen StengerInstitute for Medical Microbiology and Hygiene, University of Ulm Medical Center, 89081 Ulm, Germany.
Kevin MellertInstitute of Pathology, University of Ulm Medical Center, 89081 Ulm, Germany.
Peter MöllerInstitute of Pathology, University of Ulm Medical Center, 89081 Ulm, Germany.
Thomas F E BarthInstitute of Pathology, University of Ulm Medical Center, 89081 Ulm, Germany.
Stephan FischerInstitute of Pharmacology and Toxicology, University of Ulm Medical Center, 89081 Ulm, Germany.ORCID 0000-0001-6862-2971
Holger BarthInstitute of Pharmacology and Toxicology, University of Ulm Medical Center, 89081 Ulm, Germany.
Universität Ulm · DE

Funding

Deutsche Forschungsgemeinschaft 251293561-SFB 1149 in combination with a CRC 1149 start-up grantDeutsche Forschungsgemeinschaft 316249678-SFB 1279 (A01 and C02)
6 · The paper itself

Abstract

C3 protein toxins produced by

Indexed as

ADP Ribose TransferasesBotulinum ToxinsDendritic CellsDose-Response Relationship, DrugEndocytosisEndosomesHeLa CellsHumansProtein TransportTime FactorsADP Ribose TransferasesBotulinum Toxinsexoenzyme C3, Clostridium botulinumC3botE174Qcellular uptakeclostridial C3 toxinsdendritic cellsfusion toxin C2IN-C3limstimulated emission depletion (STED)super-resolution microscopy

Identifiers

PMID32883045
PMCPMC7551598
OpenAlexW3081748689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.