Evidence map›Paper›PMID 32883015›Full record

ArticleSensors (Basel, Switzerland)2020

Integrated Lab-on-a-Chip Optical Biosensor Using Ultrathin Silicon Waveguide SOI MMI Device.

Mohamed Y Elsayed, Sherif M Sherif, Amina S Aljaber, Mohamed A Swillam

Abstract readLetter
In one paragraph

Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohamed Y ElsayedInstitute of Biomedical Engineering (BME), University of Toronto, Toronto, ON M5S 3E2, Canada.
Sherif M SherifDepartment of Chemistry and Earth Sciences, College of Arts and Sciences, Qatar University, Doha 2713, Qatar.ORCID 0000-0003-3997-1739
Amina S AljaberDepartment of Chemistry and Earth Sciences, College of Arts and Sciences, Qatar University, Doha 2713, Qatar.
Mohamed A SwillamSchool of Science and Engineering, Department of Physics, The American University in Cairo, New Cairo 11835, Egypt.

Funding

American University in Cairo Internal FundQatar National Research Fund NPRP 8-1912-1-354
6 · The paper itself

Abstract

Waveguides with sub-100 nm thickness offer a promising platform for sensors. We designed and analyzed multimode interference (MMI) devices using these ultrathin platforms for use as biosensors. To verify our design methodology, we compared the measured and simulated spectra of fabricated 220-nm-thick MMI devices. Designs of the MMI biosensors based on the sub-100 nm platforms have been optimized using finite difference time domain simulations. At a length of 4 mm, the 50-nm-thick MMI sensor provides a sensitivity of roughly 420 nm/RIU and with a figure of merit (FOM) definition of sensitivity/full-width-at-half-maximum, the FOM is 133. On the other hand, using a thickness of 70 nm results in a more compact design-only 2.4 mm length was required to achieve a similar FOM, 134, with a sensitivity of 330 nm/RIU. The limits of detection (LOD) were calculated to be 7.1 × 10

Indexed as

Biosensing TechniquesLab-On-A-Chip DevicesSiliconEquipment DesignLimit of DetectionSiliconmultimode interferenceoptical biosensorsultrathin silicon waveguides

Identifiers

PMID32883015
PMCPMC7506679

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.