Evidence map›Paper›PMID 32883004›Full record

ArticleMicroorganisms2020

Coxsackievirus-B4 Infection Can Induce the Expression of Human Endogenous Retrovirus W in Primary Cells.

Arthur Dechaumes, Antoine Bertin, Famara Sane, Sandrine Levet, Jennifer Varghese, Benjamin Charvet, Valéry Gmyr, Julie Kerr-Conte, Justine Pierquin, Govindakarnavar Arunkumar and 3 more

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Review
  3. Human Endogenous Retroviruses Expression in Autoimmunity.The Yale journal of biology and medicine · 2024
    Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Arthur DechaumesLaboratoire de Virologie ULR3610 Univ Lille, CHU Lille, 59000 Lille, France.
Antoine BertinLaboratoire de Virologie ULR3610 Univ Lille, CHU Lille, 59000 Lille, France.
Famara SaneLaboratoire de Virologie ULR3610 Univ Lille, CHU Lille, 59000 Lille, France.
Sandrine LevetGeneuro Innovation, 69008 Lyon, France.
Jennifer VargheseLaboratoire de Virologie ULR3610 Univ Lille, CHU Lille, 59000 Lille, France.
Benjamin CharvetGeneuro Innovation, 69008 Lyon, France.
Valéry GmyrU1190 Univ Lille, Inserm, CHU Lille, European Genomic Institute for Diabetes, 59000 Lille, France.
Julie Kerr-ConteU1190 Univ Lille, Inserm, CHU Lille, European Genomic Institute for Diabetes, 59000 Lille, France.
Justine PierquinGeneuro Innovation, 69008 Lyon, France.
Govindakarnavar ArunkumarManipal Institute of Virology, Manipal Academy of Higher Education, Karnataka 576104, India.
François PattouU1190 Univ Lille, Inserm, CHU Lille, European Genomic Institute for Diabetes, 59000 Lille, France.
Hervé PerronGeneuro Innovation, 69008 Lyon, France.
Didier HoberLaboratoire de Virologie ULR3610 Univ Lille, CHU Lille, 59000 Lille, France.
Centre Hospitalier Universitaire de Lille · FREuropean Genomic Institute for Diabetes · FRManipal Academy of Higher Education · INUniversité de Lille · FRHES-SO Genève · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human Endogenous Retrovirus W Envelope (HERV-W ENV) mRNA or protein can be found in peripheral blood mononuclear cells (PBMCs) and exocrine pancreas of patients with type 1 diabetes (T1D). Further, previous observations have shown an association between enteroviral infection and development of T1D; specifically, coxsackievirus-B (CV-B) has been detected in the blood and pancreas of patients with T1D. Notably, viruses can activate HERV-W expression. Hence, we evaluated the effect of CV-B4 infection on HERV-W

Indexed as

endogenous retrovirusenterovirusmacrophagespancreatic cellsPBMCs

Identifiers

PMID32883004
PMCPMC7563422
OpenAlexW3082570539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.