Evidence map›Paper›PMID 32882929›Full record

ArticleInternational journal of molecular sciences2020

Cellular Signaling and Anti-Apoptotic Effects of Prolactin-Releasing Peptide and Its Analog on SH-SY5Y Cells.

Anna Zmeškalová, Andrea Popelová, Aneta Exnerová, Blanka Železná, Jaroslav Kuneš, Lenka Maletínská

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Peptidergic Systems and Neuroblastoma.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anna ZmeškalováInstitute of Organic Chemistry and Biochemistry, AS CR, Prague 16000, Czech Republic.
Andrea PopelováInstitute of Organic Chemistry and Biochemistry, AS CR, Prague 16000, Czech Republic.
Aneta ExnerováInstitute of Organic Chemistry and Biochemistry, AS CR, Prague 16000, Czech Republic.
Blanka ŽeleznáInstitute of Organic Chemistry and Biochemistry, AS CR, Prague 16000, Czech Republic.
Jaroslav KunešInstitute of Organic Chemistry and Biochemistry, AS CR, Prague 16000, Czech Republic.
Lenka MaletínskáInstitute of Organic Chemistry and Biochemistry, AS CR, Prague 16000, Czech Republic.

Funding

Akademie Věd České Republiky RVO:61388963Grantová Agentura České Republiky 20-00546S
6 · The paper itself

Abstract

Prolactin-releasing peptide (PrRP), a natural ligand for the GPR10 receptor, is a neuropeptide with anorexigenic and antidiabetic properties. Due to its role in the regulation of food intake, PrRP is a potential drug for obesity treatment and associated type 2 diabetes mellitus (T2DM). Recently, the neuroprotective effects of lipidized PrRP analogs have been proven. In this study, we focused on the molecular mechanisms of action of natural PrRP31 and its lipidized analog palm

Indexed as

ApoptosisApoptosis Regulatory ProteinsHumansNeuroblastomaNeuropeptidesNeuroprotective AgentsProlactin-Releasing HormoneSignal TransductionTumor Cells, CulturedApoptosis Regulatory ProteinsNeuropeptidesNeuroprotective AgentsProlactin-Releasing Hormonecellular signalinginhibitorsmethylglyoxalneuroprotectionprimary neuronal cultureprolactin-releasing peptideSH-SY5Y

Identifiers

PMID32882929
PMCPMC7503370

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.