Evidence map›Paper›PMID 32882888›Full record

ReviewPharmaceuticals (Basel, Switzerland)2020

Zinc(II)-The Overlooked Éminence Grise of Chloroquine's Fight against COVID-19?

Aleksandra Hecel, Małgorzata Ostrowska, Kamila Stokowa-Sołtys, Joanna Wątły, Dorota Dudek, Adriana Miller, Sławomir Potocki, Agnieszka Matera-Witkiewicz, Alicia Dominguez-Martin, Henryk Kozłowski and 1 more

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Zinc pyrithione is a potent inhibitor of PLJournal of enzyme inhibition and medicinal chemistry · 2022
    Article
  5. Review
  6. Review
  7. Development of Metal Complexes for Treatment of Coronaviruses.International journal of molecular sciences · 2022
    Article
  8. Article
  9. Article
  10. Structural biology of SARS-CoV-2: open the door for novel therapies.Signal transduction and targeted therapy · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Aleksandra HecelFaculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383 Wroclaw, Poland.ORCID 0000-0002-4314-9599
Małgorzata OstrowskaFaculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383 Wroclaw, Poland.
Kamila Stokowa-SołtysFaculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383 Wroclaw, Poland.
Joanna WątłyFaculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383 Wroclaw, Poland.
Dorota DudekFaculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383 Wroclaw, Poland.ORCID 0000-0002-4699-7665
Adriana MillerFaculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383 Wroclaw, Poland.
Sławomir PotockiFaculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383 Wroclaw, Poland.
Agnieszka Matera-WitkiewiczScreening Laboratory of Biological Activity Tests and Collection of Biological Material, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211A, 50-556 Wroclaw, Poland.
Alicia Dominguez-MartinDepartment of Inorganic Chemistry, Faculty of Pharmacy, University of Granada, E-18071 Granada, Spain.
Henryk KozłowskiFaculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383 Wroclaw, Poland.
Magdalena Rowińska-ŻyrekFaculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383 Wroclaw, Poland.ORCID 0000-0002-0425-1128

Funding

Narodowe Centrum Nauki UMO-2017/26/A/ST5/00363Narodowe Centrum Nauki UMO-2017/26/A/ST5/00364
6 · The paper itself

Abstract

Zn(II) is an inhibitor of

Indexed as

2019-nCoVchloroquineCOVID-19hydroxy- chloroquineSARS-CoV-2Zn(II) ionophores

Identifiers

PMID32882888
PMCPMC7558363

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.