Evidence map›Paper›PMID 32882426›Full record

ArticleClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2021

Exercise Training Reverses Gut Dysbiosis in Patients With Biopsy-Proven Nonalcoholic Steatohepatitis: A Proof of Concept Study.

Alexa Hughes, Jessica Dahmus, Gloriany Rivas, Breianna Hummer, Jeremy R Chen See, Justin R Wright, Regina Lamendella, Kathryn H Schmitz, Christopher Sciamanna, Mack Ruffin and 3 more

Abstract read
In one paragraph

Article in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Nonalcoholic Fatty Liver Disease and the Intestinal Microbiome: An Inseparable Link.Journal of clinical and translational hepatology · 2023
    Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Aerobic Exercise in the Management of Metabolic Dysfunction Associated Fatty Liver Disease.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alexa HughesMilton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, Pennsylvania.
Jessica DahmusDivision of Gastroenterology and Hepatology, Department of Medicine, Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, Pennsylvania.
Gloriany RivasDivision of Gastroenterology and Hepatology, Department of Medicine, Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, Pennsylvania.
Breianna HummerDivision of Gastroenterology and Hepatology, Department of Medicine, Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, Pennsylvania.
Jeremy R Chen SeeWright Laboratories, Juniata, Pennsylvania.
Justin R WrightWright Laboratories, Juniata, Pennsylvania.
Regina LamendellaDepartment of Biology, Juniata College, Juniata, Pennsylvania.
Kathryn H SchmitzDepartment of Public Health Sciences, Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, Pennsylvania; Department of Kinesiology, Penn State College of Health and Human Medicine, Hershey, Pennsylvania; Department of Physical Medicine and Rehabilitation, Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, Pennsylvania; Cancer Institute, Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, Pennsylvania.
Christopher SciamannaDepartment of Public Health Sciences, Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, Pennsylvania; Cancer Institute, Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, Pennsylvania; Department of Medicine, The Pennsylvania State University- Milton S. Hershey Medical Center, Hershey, Pennsylvania.
Mack RuffinDivision of Family and Community Medicine, Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, Pennsylvania.
Andrew D PattersonDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania.
Rohit LoombaDivision of Gastroenterology and Hepatology, Department of Medicine, University of California, San Diego, San Diego, California; NAFLD Research Center, University of California, San Diego, San Diego, California.
Jonathan G StineDivision of Gastroenterology and Hepatology, Department of Medicine, Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, Pennsylvania; Department of Public Health Sciences, Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, Pennsylvania; Cancer Institute, Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, Pennsylvania; Liver Center, Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, Pennsylvania. Electronic address: jstine@pennstatehealth.psu.edu.

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
Penn State Clinical and Translational Science InstituteUL1TR000127 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$17.1M
NCATS NIH HHS UL1 TR000127NCATS NIH HHS UL1 TR002014NIDDK NIH HHS L30 DK118601
6 · The paper itself

Abstract

Nonalcoholic fatty liver disease is the leading cause of liver disease worldwide and can progress to nonalcoholic steatohepatitis (NASH) through physical inactivity and gut dysbiosis.

Indexed as

Gastrointestinal MicrobiomeNon-alcoholic Fatty Liver DiseaseAnimalsBiopsyDysbiosisExerciseHumansLiverProof of Concept Study

Identifiers

PMID32882426
PMCPMC9067391

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.