ArticleJournal of pain and symptom management2021
Psychological Distress in Bereaved Caregivers of Patients With Advanced Cancer.
Article in Journal of pain and symptom management, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Emotion Regulation Interventions for Cancer Patients and Their Relatives: A Systematic Review.Cancer medicine · 2026Pooled it
- Therapeutic intervention in fear of cancer recurrence in adult oncology patients: a systematic review.Journal of cancer survivorship : research and practice · 2023Pooled it
- Trial
- Empathy and Humanistic Care Ability in Oncology Nurses: The Mediating Role of Emotional Intelligence.Journal of advanced nursing · 2026Article
- Associations between depressive symptoms, attachment style, and continuing bonds among Japanese bereaved family members of patients with cancer: a nationwide cross-sectional study.BMC psychology · 2026Article
- Evaluating an AI-Enabled Mobile Mental Health Monitoring Tool Among Family Caregivers of Adults Living With Cancer: Single-Arm Feasibility and Acceptability Trial Protocol.JMIR research protocols · 2026Article
- Frailty and neuropathy in chemotherapy patients: moderated mediation roles of fatigue and mindfulness on CIPN, anxiety, and depression.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- A nature-based intervention for bereaved friend and family cancer caregivers: a study protocol.Frontiers in public health · 2026Article
- Navigating parenthood and a partner's terminal cancer: subgroup analysis of the course of psychological distress within a comprehensive support program for families with parental cancer (Family-SCOUT).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- From Fear to Hope: Understanding Preparatory and Anticipatory Grief in Women with Cancer-A Public Health Approach to Integrating Screening, Compassionate Communication, and Psychological Support Strategies.Journal of clinical medicine · 2025Review
- Ethical dilemmas and the reconstruction of subjectivity in digital mourning in the age of AI: an empirical study on the acceptance intentions of bereaved family members of cancer patients.Frontiers in digital health · 2025Article
- Risk of mental health conditions in bereavement: a population-based analysis of lung cancer spouses.Frontiers in public health · 2025Article
- Preparing for Cancer: A Qualitative Study of Hispanic Patient and Caregiver Needs.Healthcare (Basel, Switzerland) · 2024Article
- Article
- Cancer caregivers are primarily motivated by love and sense of duty.Health psychology research · 2024Article
- Effects of Music on the Quality of Life of Family Caregivers of Terminal Cancer Patients: A Randomised Controlled Trial.Healthcare (Basel, Switzerland) · 2023Article
- Acceptance of Caregiver-Patient Support to Latinx Coping with Advanced Cancer (CASA) Intervention: A Caregiver Case Study.International journal of environmental research and public health · 2023Article
- Prevalence and Associated Factors of Depressive Symptoms in Bereaved Family Members of Terminally Ill Cancer Patients Receiving Home Care.Palliative medicine reportsArticle
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
contextIndividuals caring for patients with advanced cancer (caregivers) experience psychological distress during the patient's illness course. However, data on the prevalence of bereaved caregivers' psychological distress and its relationship with the quality of patient's end of life (EOL) care are limited.
objectivesTo describe rates of depression and anxiety symptoms in bereaved caregivers of patients with advanced cancer and to understand the relationship between these outcomes and patient distress at the EOL.
methodsWe conducted a secondary analysis of 168 caregivers enrolled in a supportive care trial for patients with incurable lung and gastrointestinal cancers and their caregivers. We used the Hospital Anxiety and Depression Scale to assess caregivers' depression and anxiety symptoms at three months after the patient's death. Caregivers also rated the patient's physical and psychological distress in the last week of life on a 10-point scale three months after the patient death. We used linear regression adjusting for caregiver age, sex, randomization, and cancer type to explore the relationship between bereaved caregivers' depression and anxiety symptoms and their ratings of physical and psychological distress in patients at the EOL.
resultsOf the 168 bereaved caregivers, 30.4% (n = 51) and 43.4% (n = 73) reported clinically significant depression and anxiety symptoms, respectively. Caregiver ratings of worse physical (B = 0.32; P = 0.009) and psychological (B = 0.50; P < 0.001) distress experienced by the patient at the EOL were associated with worse depression symptoms in bereaved caregivers. Only caregiver rating of worse psychological distress experienced by the patient at the EOL (B = 0.42; P < 0.001) was associated with worse bereaved caregivers' anxiety symptoms.
conclusionMany bereaved caregivers of patients with advanced cancer experience symptoms of depression and anxiety, which are associated with their perceptions of distress in their loved ones at the EOL.
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