ArticleThe Journal of infection2020
The estimation of diagnostic accuracy of tests for COVID-19: A scoping review.
Article in The Journal of infection, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Evaluation of Diagnostic Strategies for Identifying SARS-CoV-2 Infection in Clinical Practice: a Systematic Review and Compliance with the Standards for Reporting Diagnostic Accuracy Studies Guideline (STARD).Microbiology spectrum · 2022Pooled it
- Classification Schemes of COVID-19 High Risk Areas and Resulting Policies: A Rapid Review.Frontiers in public health · 2022Pooled it
- Utility of Routine Laboratory Biomarkers to Detect COVID-19: A Systematic Review and Meta-Analysis.Viruses · 2021Pooled it
- Diagnostic accuracy of non-invasive SARS-CoV-2 screening tests: a national prospective analysis.BMC infectious diseases · 2025Trial
- Lung ultrasound is cost-effective for early diagnosis of COVID-19 pneumonia in primary care.BMC pulmonary medicine · 2025Article
- Higher Post-Acute Health Care Costs Following SARS-CoV-2 Infection Among Adults in Ontario, Canada.Journal of multidisciplinary healthcare · 2024Article
- Pitfalls and biases in neuroepidemiological studies of COVID-19 and the nervous system: a critical appraisal of the current evidence and future directions.Journal of neurology · 2023Review
- SARS-CoV-2 Diagnosis Using Transcriptome Data: A Machine Learning Approach.SN computer science · 2023Article
- Sensitivity and Diagnostic Yield of the First SARS-CoV-2 Nucleic Acid Amplification Test Performed for Patients Presenting to the Hospital.JAMA network open · 2022Article
- Electrochemical biosensors for SARS-CoV-2 detection: Voltametric or impedimetric transduction?Bioelectrochemistry (Amsterdam, Netherlands) · 2022Review
- Clinical evaluation of the GSD NovaPrime® SARS-CoV-2 RTq-PCR assay.Diagnostic microbiology and infectious disease · 2022Article
- Review
- Chasing the storm: Recruiting non-hospitalized patients for a multi-site randomized controlled trial in the United States during the COVID-19 pandemic.Clinical and translational science · 2022Review
- Potential diagnosis of COVID-19 from chest X-ray and CT findings using semi-supervised learning.Physical and engineering sciences in medicine · 2022Article
- Nanobiosensor-based diagnostic tools in viral infections: Special emphasis on Covid-19.Reviews in medical virology · 2022Review
- COVID-19 diagnosis by SARS-CoV-2 Spike protein detection in saliva using an ultrasensitive magneto-assay based on disposable electrochemical sensor.Sensors and actuators. B, Chemical · 2022Article
- Saliva-based detection of COVID-19 infection in a real-world setting using reagent-free Raman spectroscopy and machine learning.Journal of biomedical optics · 2022Article
- Challenges and complexities in evaluating severe acute respiratory syndrome coronavirus 2 molecular diagnostics during the COVID-19 pandemic.African journal of laboratory medicine · 2022Article
- Article
- Dogs Detecting COVID-19 From Sweat and Saliva of Positive People: A Field Experience in Mexico.Frontiers in medicine · 2022Article
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6 authors.
Funding
Abstract
objectivesTo assess the methodologies used in the estimation of diagnostic accuracy of SARS-CoV-2 real-time reverse transcription polymerase chain reaction (rRT-PCR) and other nucleic acid amplification tests (NAATs) and to evaluate the quality and reliability of the studies employing those methods.
methodsWe conducted a systematic search of English-language articles published December 31, 2019-June 19, 2020. Studies of any design that performed tests on ≥10 patients and reported or inferred correlative statistics were included. Studies were evaluated using elements of the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) guidelines.
resultsWe conducted a narrative and tabular synthesis of studies organized by their reference standard strategy or comparative agreement method, resulting in six categorizations. Critical study details were frequently unreported, including the mechanism for patient/sample selection and researcher blinding to results, which lead to concern for bias.
conclusionsCurrent studies estimating test performance characteristics have imperfect study design and statistical methods for the estimation of test performance characteristics of SARS-CoV-2 tests. The included studies employ heterogeneous methods and overall have an increased risk of bias. Employing standardized guidelines for study designs and statistical methods will improve the process for developing and validating rRT-PCR and NAAT for the diagnosis of COVID-19.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.