Evidence map›Paper›PMID 32882216›Full record

ReviewEuropean journal of pharmacology2020

The prophylaxis and treatment potential of supplements for COVID-19.

Adeleh Sahebnasagh, Fatemeh Saghafi, Razieh Avan, Amirhosein Khoshi, Masoud Khataminia, Mohammadreza Safdari, Solomon Habtemariam, Hassan Rezai Ghaleno, Seyed Mohammad Nabavi

Erratum issuedOpen access · greenAbstract readReview
In one paragraph

Review in European journal of pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 49 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Combined Metabolic Activators Accelerates Recovery in Mild-to-Moderate COVID-19.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Trial
  4. Review
  5. Review
  6. Review
  7. Anti-COVID-19 potential ofScientific African · 2022
    Review
  8. Maoto, a traditional herbal medicine, for post-exposure prophylaxis for Japanese healthcare workers exposed to COVID-19: A single center study.Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy · 2022
    Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 2 countries.

Adeleh SahebnasaghClinical Research Center, Department of Internal Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran. Electronic address: masoomehsahebnasagh@gmail.com.
Fatemeh SaghafiDepartment of Clinical Pharmacy, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Electronic address: saghafi.fa@gmail.com.
Razieh AvanDepartment of Clinical Pharmacy, Medical Toxicology and Drug Abuse Research Center (MTDRC), Faculty of Pharmacy, Birjand University of Medical Sciences, Birjand, Iran. Electronic address: avanr91@gmail.com.
Amirhosein KhoshiDepartment of Clinical Biochemistry, School of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran. Electronic address: ahkh83@gmail.com.
Masoud KhataminiaStudent Research Committee, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: masoodkhataminia@yahoo.com.
Mohammadreza SafdariDepartment of Orthopedic Surgery, Faculty of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran. Electronic address: safdari57@yahoo.com.
Solomon HabtemariamPharmacognosy Research Laboratories and Herbal Analysis Services UK, University of Greenwich, Central Avenue, Chatham-Maritime, Kent, ME4 4TB, United Kingdom. Electronic address: s.habtemariam@herbalanalysis.co.uk.
Hassan Rezai GhalenoDepartment of Surgery, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran. Electronic address: Hassan_Rezai2020@yahoo.com.
Seyed Mohammad NabaviApplied Biotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran; Division of Translational Medicine, Baqiyatallah Hospital, Baqiyatallah University of Medical Sciences, Tehran, Iran. Electronic address: Nabavi208@gmail.com.
North Khorasan University of Medical Sciences · IRBiotechnology Research Center · IRBirjand University of Medical Sciences · IRLorestan University of Medical Sciences · IRPharmaceutical Sciences Research CenterTehran University of Medical Sciences · IRUniversity of Greenwich · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global impact of the new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), infection that caused COVID-19 has been evident in the last few months from the unprecedented socioeconomic disruption to more than 600,000 deaths. The lack of vaccine and effective therapeutic agents for the disease prompted world-wide effort to test those antiviral therapeutics already in use for other diseases. Another interesting approach has been based on the pathological sequel of the disease that involve severe inflammatory reaction (or the cytokine storm) associated with pneumonia in critically ill patients. This article outlines the prophylaxis therapeutic potential of supplements vitamins and micronutrients in COVID-19. By ameliorating the inflammatory and oxidative stress associated with the disease and some direct antiviral effects, the application of these agents as adjuvants and other alternative approaches are discussed. Available clinical trials including those currently registered on these supplements are scrutinized.

Indexed as

Dietary SupplementsAnimalsAntioxidantsCoronavirus InfectionsCOVID-19HumansPandemicsPneumonia, ViralVitaminsAntioxidantsVitaminsAdjuvant therapyCoronavirusCOVID-19SupplementsVitamins

Identifiers

PMID32882216
PMCPMC7462519
OpenAlexW3081988996

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.