Evidence map›Paper›PMID 32881915›Full record

ArticlePloS one2020

An exploratory study of predictors of cognition in two low-income samples of infants across the first year of life.

Viviane Valdes, Lara J Pierce, Christianne Joy Lane, Emily B Reilly, Sarah K G Jensen, Alma Gharib, Pat Levitt, Charles A Nelson, Barbara L Thompson

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Progressions on the Coexistence of Neuronal and Glial Precursor Cells in the Cerebral Ventricular Zone.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Viviane ValdesDepartment of Pediatrics, Division of Developmental Medicine, Boston Children's Hospital, Boston, Massachusetts, United States of America.
Lara J PierceDepartment of Pediatrics, Division of Developmental Medicine, Boston Children's Hospital, Boston, Massachusetts, United States of America.
Christianne Joy LaneDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
Emily B ReillyDepartment of Pediatrics, Division of Developmental Medicine, Boston Children's Hospital, Boston, Massachusetts, United States of America.
Sarah K G JensenDepartment of Pediatrics, Division of Developmental Medicine, Boston Children's Hospital, Boston, Massachusetts, United States of America.
Alma GharibDepartment of Pediatrics, Children's Hospital Los Angeles, Los Angeles, California, United States of America.ORCID 0000-0002-7588-407X
Pat LevittDepartment of Pediatrics, Children's Hospital Los Angeles, Los Angeles, California, United States of America.
Charles A NelsonDepartment of Pediatrics, Division of Developmental Medicine, Boston Children's Hospital, Boston, Massachusetts, United States of America.
Barbara L ThompsonDepartment of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States of America.ORCID 0000-0002-7294-3900
Boston Children's Hospital · USUniversity of Southern California · USMichigan United · US

Funding

Southern California Clinical and Translational Science InstituteUL1TR001855 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Thomas A Buchanan, Michele D. Kipke · 2016 to 2026
$81.3M
Southern California Clinical and Translational Science InstituteUL1TR000130 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BUCHANAN, THOMAS A · 2012 to 2015
$36.0M
NCATS NIH HHS UL1 TR000130NCATS NIH HHS UL1 TR001855
6 · The paper itself

Abstract

objectiveIn this exploratory longitudinal study we assessed cognitive development in a community sample of infants born into predominantly low-income families from two different urban sites, to identify family and community factors that may associate with outcomes by 1 year of age.

methodInfant-mother dyads (n = 109) were recruited in Boston and Los Angeles community pediatric practices. Infant cognition was measured using the Mullen Scales of Early Learning when the infant was aged 2, 6, 9, and 12 months. Longitudinal linear mixed effects modeling and linear regression models explored potential predictors of cognitive outcomes.

resultsCognitive scores were lower than the reference population mean at both 6 and 12 months. There were site differences in demographics and cognitive performance. Maternal education predicted expressive language in Boston, and speaking Spanish and lower rates of community poverty were associated with greater increases in overall cognition in Los Angeles.

conclusionThis exploratory study identified a number of drivers of child development that are both shared across cohorts and unique to specific community samples. Factors influencing heterogeneity within and across populations both may be important contributors to prevention and intervention in supporting healthy development among children.

Indexed as

Child DevelopmentCognitionPovertyBostonFemaleHumansInfantLongitudinal StudiesLos AngelesMothers

Identifiers

PMID32881915
PMCPMC7470325
OpenAlexW3083123471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.