Evidence map›Paper›PMID 32881877›Full record

ArticlePloS one2020

Hepatitis C prevalence in Denmark in 2016-An updated estimate using multiple national registers.

Stine Nielsen, Janne Fuglsang Hansen, Gordon Hay, Susan Cowan, Peter Jepsen, Lars Haukali Omland, Henrik Bygum Krarup, Jacob Søholm, Jeffrey V Lazarus, Nina Weis and 2 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Cirrhosis epidemiology in Denmark 1998-2022, and 2030 forecast.JHEP reports : innovation in hepatology · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Hepatitis C time trends in reported cases and estimates of the hidden population born before 1965, Denmark and Sweden, 1990 to 2020.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2022
    Article
  9. Management of liver diseases: Current perspectives.World journal of gastroenterology · 2022
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Lower Incidence of Hepatobiliary Cancer inJournal of clinical and experimental hepatology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 3 countries.

Stine NielsenDepartment of Infectious Diseases, Odense University Hospital, Odense, Denmark.ORCID 0000-0002-5931-5379
Janne Fuglsang HansenDepartment of Infectious Diseases, Odense University Hospital, Odense, Denmark.
Gordon HayCentre for Public Health, Liverpool John Moores University, Liverpool, United Kingdom.
Susan CowanDepartment of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark.
Peter JepsenDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.
Lars Haukali OmlandDepartment of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet, Denmark.
Henrik Bygum KrarupDepartment of Molecular Diagnostics, Aalborg University Hospital, Aalborg, Denmark.ORCID 0000-0001-5294-2428
Jacob SøholmDepartment of Infectious Diseases, Odense University Hospital, Odense, Denmark.
Jeffrey V LazarusBarcelona Institute for Global Health (ISGlobal), Hospital Clínic, University of Barcelona, Barcelona, Spain.ORCID 0000-0001-9618-2299
Nina WeisDepartment of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.
Anne ØvrehusDepartment of Infectious Diseases, Odense University Hospital, Odense, Denmark.
Peer Brehm ChristensenDepartment of Infectious Diseases, Odense University Hospital, Odense, Denmark.ORCID 0000-0003-1394-058X
Odense University Hospital · DKUniversity of Southern Denmark · DKAalborg University Hospital · DKAarhus University Hospital · DKBarcelona Institute for Global Health · ESCopenhagen University Hospital · DKLiverpool John Moores University · GBStatens Serum Institut · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic hepatitis C (CHC) can be eliminated as a public health threat by meeting the WHO targets: 90% of patients diagnosed and 80% treated by 2030. To achieve and monitor progress towards elimination, an updated estimate of the size of the CHC population is needed, but Denmark has no complete national CHC register. By combining existing registers in 2007, we estimated the population living with CHC to be 16,888 (0.38% of the adult population).

aimTo estimate the population living with diagnosed and undiagnosed CHC in Denmark on 31 December 2016. Among additional aims were to estimate the proportion of patients attending specialised clinical care.

methodsPeople with diagnosed CHC were identified from four national registers. The total diagnosed population was estimated by capture-recapture analysis. The undiagnosed population was estimated by comparing the register data with data from two cross-sectional surveys.

resultsThe population living with diagnosed CHC in Denmark was 7,581 persons (95%CI: 7,416-12,661) of which 6,116 (81%) were identified in the four registers. The estimated undiagnosed fraction was 24%, so the total CHC infected population was 9,975 corresponding to 0.21% of the adult population (95%CI: 9,758-16,659; 0.21%-0.36%). Only 48% of diagnosed patients had received specialised clinical care.

conclusionCHC prevalence in Denmark is declining and 76% of patients have been diagnosed. Linking diagnosed patients to care and increasing efforts to test people with former or current drug use will be necessary to achieve CHC elimination.

Indexed as

AdultCross-Sectional StudiesDatabases, FactualDenmarkFemaleHepatitis C, ChronicHumansMaleMiddle AgedRegistries

Identifiers

PMID32881877
PMCPMC7470322
OpenAlexW3083230695

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.