ArticleThe Journal of head trauma rehabilitation
Associations Between Neurochemistry and Gait Performance Following Concussion in Collegiate Athletes.
Article in The Journal of head trauma rehabilitation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed, 17 citations in OpenAlex.
- Evaluating Associations Between Postconcussion Physical Activity and Brain Neurometabolite Concentrations in the Posterior Cingulate Gyrus.Journal of child neurology · 2026Article
- Article
- Prefrontal Cortex Activity During Gait in People With Persistent Symptoms After Concussion.Neurorehabilitation and neural repair · 2024Article
- Impaired Neuromotor Control During Gait in Concussed Adolescents-A Frequency Analysis.Journal of applied biomechanics · 2024Article
- Prefrontal Glutathione Levels in Major Depressive Disorder Are Linked to a Lack of Positive Affect.Brain sciences · 2023Article
- The effects of sports-related concussion history on female adolescent brain activity and connectivity for bilateral lower extremity knee motor control.Psychophysiology · 2023Article
- Virtual reality-based interventions for the rehabilitation of vestibular and balance impairments post-concussion: a scoping review.Journal of neuroengineering and rehabilitation · 2023Article
- Loss of Motor Stability After Sports-Related Concussion: Opportunities for Motor Learning Strategies to Reduce Musculoskeletal Injury Risk.Sports medicine (Auckland, N.Z.) · 2021Review
Corrections and comments
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Authors and funding
10 authors at 1 institution in 2 countries.
Funding
Abstract
objectiveTo evaluate the strength of associations between single-task and dual-task gait measures and posterior cingulate gyrus (PCG) neurochemicals in acutely concussed collegiate athletes.
settingParticipants were recruited from an NCAA Division 1 University.
participantsNineteen collegiate athletes acutely (<4 days) following sports-related concussion.
designWe acquired magnetic resonance spectroscopy (MRS) in the PCG and gait performance measurements in the participants, acutely following concussion. Linear mixed-effects models were constructed to measure the effect of gait performance, in the single- and dual-task settings, and sex on the 6 neurochemicals quantified with MRS in mmol. Correlation coefficients were also calculated to determine the direction and strength of the relationship between MRS neurochemicals and gait performance, postconcussion symptom score, and number of previous concussions. MAIN MEASURES: Average gait speed, average cadence, N-acetyl aspartate, choline, myo-inositol, glutathione, glutamate plus glutamine, and creatine.
resultsSingle-task gait speed (P = .0056) and cadence (P = .0065) had significant effects on myo-inositol concentrations in the PCG, independent of sex, in concussed collegiate athletes. Single-task cadence (P = .047) also had a significant effect on glutathione in the PCG. No significant effects were observed between dual-task gait performance and PCG neurochemistry.
conclusionsThese findings indicate that increased concentrations of neuroinflammatory markers in the PCG are associated with slower single-task gait performance within 4 days of sports-related concussion.
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Registered trials
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